CAS 681511-84-2

Benzamide,3-[[4-[[(1R)-2,2-dimethyl-1-(5-methyl-2-furanyl)propyl]amino]-1,1-dioxido-1,2,5-thiadiazol-3-yl]amino]-2-hydroxy-N,N-dimethyl-

Description:

Benzamide, 3-[[4-[[(1R)-2,2-dimethyl-1-(5-methyl-2-furanyl)propyl]amino]-1,1-dioxido-1,2,5-thiadiazol-3-yl]amino]-2-hydroxy-N,N-dimethyl- (CAS 681511-84-2) is a complex organic compound characterized by its unique structural features, including a benzamide core and multiple functional groups. The presence of a thiadiazole ring contributes to its potential biological activity, while the dimethylamino and hydroxy groups enhance its solubility and reactivity. The compound is likely to exhibit polar characteristics due to these functional groups, which may influence its interactions in biological systems. Additionally, the furan moiety suggests potential for aromatic interactions, which can be significant in drug design and molecular recognition. The stereochemistry indicated by the (1R) configuration suggests specific spatial arrangements that could affect the compound's pharmacological properties. Overall, this compound may have applications in medicinal chemistry, particularly in the development of therapeutics targeting specific biological pathways. However, detailed studies would be necessary to fully elucidate its properties and potential uses.

Formula: C₂₁H₂₇N₅O₅S

Synonyms:

• Benzamide, 3-[[4-[[(1R)-2,2-dimethyl-1-(5-methyl-2-furanyl)propyl]amino]-1,1-dioxido-1,2,5-thiadiazol-3-yl]amino]-2-hydroxy-N,N-dimethyl-

SLW131

CAS: 681511-84-2

SLW131 (Compound 10) is a CCR7 antagonist with strong affinity, showing a Ki of 9.85 nM. It inhibits CCL19-induced Go protein activation with an IC50 of 29.4 μM and β-arrestin2 recruitment with an IC50 of 6.0 μM. SLW131 also suppresses CCL19-induced morphological changes in primary BMDC cells and CCR7-mediated migration of mouse CD4+ T cells.

Formula: C₂₁H₂₇N₅O₅S

Color and Shape: Solid

Molecular weight: 461.535

Ref: TM-T205065