CAS 68223-96-1

N-T-boc-leu-gly-arg P-nitroanilide

Description:

N-T-boc-leu-gly-arg P-nitroanilide is a synthetic peptide derivative commonly used in biochemical research, particularly in the study of proteolytic enzymes. The compound features a tert-butyloxycarbonyl (Boc) protecting group on the leucine residue, which aids in the stability and solubility of the peptide during synthesis and manipulation. The presence of the P-nitroanilide moiety serves as a chromogenic substrate, allowing for the quantification of enzymatic activity through colorimetric assays. This compound is typically characterized by its ability to undergo cleavage by specific proteases, releasing the P-nitroaniline product, which can be measured spectrophotometrically. Its structure includes a sequence of amino acids—leucine, glycine, and arginine—contributing to its biochemical properties. N-T-boc-leu-gly-arg P-nitroanilide is generally stable under standard laboratory conditions but should be handled with care, as with all chemical substances, to avoid degradation or unwanted reactions.

Formula: C₂₅H₄₀N₈O₇

InChI: InChI=1/C25H40N8O7/c1-15(2)13-19(31-24(37)40-25(3,4)5)21(35)29-14-20(34)32-22(36)18(7-6-12-28-23(26)27)30-16-8-10-17(11-9-16)33(38)39/h8-11,15,18-19,30H,6-7,12-14H2,1-5H3,(H,29,35)(H,31,37)(H4,26,27,28)(H,32,34,36)/t18-,19-/m0/s1

SMILES: CC(C)C[C@@H](C(=NCC(=NC(=O)[C@H](CCCNC(=N)N)Nc1ccc(cc1)N(=O)=O)O)O)N=C(O)OC(C)(C)C

Synonyms:

• Butyloxycarbonyl-leucyl-glycyl-arginine-4-nitroanilide
• Butyloxycarbonyl-leucyl-glycyl-arginyl-para-nitroanilide
• N-tert-Butoxycarbonyl-L-leucyl-L-glycyl-L-arginine-p-nitroaniline
• L-Argininamide, N-((1,1-dimethylethoxy)carbonyl)-L-leucylglycyl-N-(4-nitrophenyl)-
• N-(tert-butoxycarbonyl)-L-leucyl-N-{(2S)-5-[(diaminomethylidene)amino]-2-[(4-nitrophenyl)amino]pentanoyl}glycinamide
• Endotoxin Substrate acetate salt Boc-Leu-Gly-Arg-pNA acetate salt
• N(tert-BOC)-leucine-glycine-arginine-p-nitroanilide
• N-T-BOC-LEU-GLY-ARG P-NITROANILIDE
• BOC-LEU-GLY-ARG-P-NITROANILIDE

Endotoxin Substrate

CAS: 68223-96-1

Boc-LGR-pNA, a chromogenic substrate for horseshoe crab clotting enzyme, which is used in quantitative assays of endotoxin.

Formula: C₂₅H₄₀N₈O₇

Purity: 99.6%

Molecular weight: 564.64

Ref: 01-4007683

Endotoxin Substrate

CAS: 68223-96-1

Endotoxin Substrate (Boc-LGR-pNA) is a chromogenic substrate utilized for the quantitative assays of endotoxin [1].

Formula: C₂₅H₄₀N₈O₇

Color and Shape: Solid

Molecular weight: 564.63

Ref: TM-T82468

Boc-Leu-Gly-Arg-pNA

CAS: 68223-96-1

a chromogenic substrate for horseshoe crab clotting enzyme, which is used in quantitative assays of endotoxin.

Formula: C₂₅H₄₀N₈O₇

Color and Shape: Powder

Molecular weight: 564.63 g/mol

Ref: 3D-FE110714