CAS 6823-69-4

2-Propenamide, 3,3'-(1,4-phenylene)bis[N-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-, dihydrochloride

Description:

2-Propenamide, 3,3'-(1,4-phenylene)bis[N-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-, dihydrochloride, with CAS number 6823-69-4, is a complex organic compound characterized by its amide functional groups and imidazole moieties. This substance typically appears as a white to off-white solid and is soluble in water due to the presence of the dihydrochloride form, which enhances its ionic character. The compound features a bis(phenyl) structure, indicating that it has two phenyl rings connected by a phenylene bridge, contributing to its stability and potential for π-π stacking interactions. The imidazole groups suggest potential biological activity, as imidazole derivatives are often found in pharmaceuticals and can interact with biological targets. Its synthesis and applications may be of interest in medicinal chemistry, particularly in the development of compounds with specific biological activities. Safety data should be consulted for handling and usage, as with any chemical substance, to ensure proper precautions are taken.

Formula: C₃₀H₂₈N₆O₂.2HCl

InChI: InChI=1S/C30H28N6O2.2ClH/c37-27(35-25-11-7-23(8-12-25)29-31-17-18-32-29)15-5-21-1-2-22(4-3-21)6-16-28(38)36-26-13-9-24(10-14-26)30-33-19-20-34-30;;/h1-16H,17-20H2,(H,31,32)(H,33,34)(H,35,37)(H,36,38);2*1H/b15-5+,16-6+;;

Synonyms:

• Gw4869
• GW 4869 (hydrochloride hydrate)
• Hydrochloride Hydrate

GW4869

CAS: 6823-69-4

Formula: C₃₀H₂₉ClN₆O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 541.0433

Ref: IN-DA00FBIT

GW4869

CAS: 6823-69-4

GW4869

Purity: ≥98%

Molecular weight: 577.5g/mol

Ref: 54-BUP02500

GW4869

CAS: 6823-69-4

Formula: C₃₀H₂₈N₆O₂·2HCl

Purity: ≥ 98.0%

Color and Shape: Light yellow to yellow powder

Molecular weight: 577.50

Ref: 7W-GL1396

GW4869 dihydrochloride

CAS: 6823-69-4

GW4869 dihydrochloride

Purity: 97%

Molecular weight: 577.50g/mol

Ref: 54-BISN0156

GW4869

CAS: 6823-69-4

GW4869 (GW69A) is a selective and non-competitive inhibitor of neutral sphingomyelinase N-SMase (IC50=1 μM).

Formula: C₃₀H₃₀Cl₂N₆O₂

Purity: 98.12% - 98.47%

Color and Shape: Solid

Molecular weight: 577.5

Ref: TM-T3640

GW4869

Controlled Product

CAS: 6823-69-4

Formula: C₃₀H₂₈N₆O₂·2HCl

Color and Shape: Neat

Ref: TR-G019355

N-SMase Inhibitor, GW4869

CAS: 6823-69-4

GW4869 is a small molecule inhibitor of N-SMase, a proton pump that regulates the intracellular pH. GW4869 has been shown to inhibit the growth of cancer cells by binding to and inhibiting the activity of N-SMase. It also inhibits inflammation in bowel disease by reducing exosome production and preventing toll-like receptor activation. GW4869 exhibits biochemical properties such as polymerase chain reaction inhibition, DNA binding activity, and protein synthesis inhibition. In vitro assays have shown its ability to bind to dna and gw4869 has been shown to reduce leukemia cell viability in mice with bone marrow transplants.

Formula: C₃₀H₂₈N₆O₂·2HCl

Purity: Min. 95%

Molecular weight: 577.5 g/mol

Ref: 3D-GAA82369