CAS 68244-58-6

orotidine 5'-monophosphate trisodium

Description:

Orotidine 5'-monophosphate trisodium, also known as orotidine monophosphate (OMP), is a nucleotide that plays a crucial role in the biosynthesis of pyrimidine nucleotides. It is a sodium salt of orotidine 5'-monophosphate, characterized by its three sodium ions that enhance its solubility in aqueous solutions. This compound is involved in the metabolic pathway of nucleic acid synthesis, serving as a precursor to uridine monophosphate (UMP), which is essential for RNA synthesis. Orotidine 5'-monophosphate is typically a white to off-white powder, and it is soluble in water, making it suitable for various biochemical applications. Its stability under physiological conditions allows it to function effectively in enzymatic reactions. Additionally, it may be used in research settings to study nucleotide metabolism and enzyme kinetics. As with many biochemical substances, proper handling and storage conditions are essential to maintain its integrity and functionality in experimental applications.

Formula: C₁₀H₁₃N₂NaO₁₁P

InChI: InChI=1/C10H13N2O11P.Na/c13-5-1-3(9(16)17)12(10(18)11-5)8-7(15)6(14)4(23-8)2-22-24(19,20)21;/h1,4,6-8,14-15H,2H2,(H,16,17)(H,11,13,18)(H2,19,20,21);

SMILES: c1c(C(=O)O)n(C2C(C(C(COP(=O)(O)O)O2)O)O)c(=O)nc1O.[Na]

Synonyms:

• 4-pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-3-(5-O-phosphonopentofuranosyl)-, monosodium salt

Orotidine 5′-monophosphate trisodium

CAS: 68244-58-6

Orotidine 5'-monophosphate trisodium, a pyrimidine nucleotide, is synthesized through the de novo DNA synthesis pathway by various microorganisms, including M.

Formula: C₁₀H₁₀N₂Na₃O₁₁P

Color and Shape: Solid

Molecular weight: 434.14

Ref: TM-T75676

Orotidine 5'-Monophosphate Trisodium Salt

CAS: 68244-58-6

Applications Orotidine 5'-Monophosphate Trisodium Salt is synthesized from the reaction of silver salt with MeI and phosphorylated with the cyanoethyl phosphate-dicyclohexylcarbodiimide reagent.
References Moffatt, J. G.: J. Am. Chem. Soc., 85, 1118-1123 (1963)

Formula: C₁₀H₁₀N₂O₁₁P·3Na

Color and Shape: Neat

Molecular weight: 434.136

Ref: TR-O691525

Orotidine 5'-monophosphate trisodium salt

CAS: 68244-58-6

Ribonuclesides is a novel nucleoside that contains the 2'-deoxyribose phosphate moiety. It is an anticancer drug that inhibits DNA synthesis and blocks viral replication. Ribonucleosides are phosphoramidites and can be used for the synthesis of DNA or RNA, which are important for cellular metabolism. Ribonucleosides also have antiviral properties and can inhibit protein synthesis by blocking the enzyme ribonucleotide reductase.

Formula: C₁₀H₁₀N₂O₁₁PNa₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 434.14 g/mol

Ref: 3D-NO71879