CAS 6829-98-7

Imipramine N-oxide

Description:

Imipramine N-oxide is a chemical compound derived from imipramine, a tricyclic antidepressant. It is characterized by the presence of an N-oxide functional group, which is formed by the oxidation of the nitrogen atom in the imipramine structure. This modification can influence the compound's pharmacological properties and its interaction with biological systems. Imipramine N-oxide is typically a white to off-white solid and is soluble in polar solvents. Its molecular structure includes a dibenzocycloheptene core, which is common in tricyclic antidepressants, and the N-oxide group can affect its binding affinity to neurotransmitter receptors. While imipramine itself is primarily used for treating depression and certain anxiety disorders, the N-oxide derivative may exhibit different therapeutic effects or side effects. Research into its specific biological activity and potential applications is ongoing, as understanding such derivatives can provide insights into drug metabolism and efficacy.

Formula: C₁₉H₂₄N₂O

InChI: InChI=1S/C19H24N2O/c1-21(2,22)15-7-14-20-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)20/h3-6,8-11H,7,12-15H2,1-2H3

InChI key: InChIKey=QZIQORUGXBPDSU-UHFFFAOYSA-N

SMILES: C(CCN(C)(C)=O)N1C=2C(CCC=3C1=CC=CC3)=CC=CC2

Synonyms:

• 10,11-Dihydro-N,N-dimethyl-5H-dibenz(b,f)azepine-5-propanamine N-oxide
• 5-(3-(Dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine 5-oxide
• 5-(3-(Dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine N-oxide
• 5H-Dibenz(b,f)azepine, 5-(3-(dimethylamino)propyl)-10,11-dihydro-, N-oxide
• 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, N-oxide
• Elepsin
• Imipramine N-oxide
• Imipramine oxide
• Imipraminoxide [INN]
• Imipraminoxido
• Imipraminoxido [INN-Spanish]
• Imipraminoxidum
• Imipraminoxidum [INN-Latin]
• N,N-dimethyl-3-(5-oxido-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propan-1-amine
• Unii-8Mks280Xjw
• [3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]dimethylamine oxide

Imipramine N-Oxide

CAS: 6829-98-7

Color and Shape: Neat

Ref: 61-FOR0077.12

Imipramine N-oxide

CAS: 6829-98-7

Imipramine N-oxide is a tricyclic antidepressant (TCA) and imipramine analogue used to treat depression.

Formula: C₁₉H₂₄N₂O

Purity: 99.80%

Color and Shape: Solid

Molecular weight: 296.41

Ref: TM-T74205

Imipramine N-Oxide

Controlled Product

CAS: 6829-98-7

Formula: C₁₉H₂₄N₂O

Color and Shape: Neat

Molecular weight: 296.41

Ref: 86-MM0077.12

Imipramine N-oxide hydrate

Controlled Product

CAS: 6829-98-7

Imipramine N-oxide hydrate is a polymer drug that belongs to the group of amines. It inhibits the activity of CYP450 enzymes and has been shown to be effective in treating inflammatory bowel disease (IBD). Imipramine N-oxide hydrate prevents adenosine A3 receptor activation and suppresses the production of dinucleotide phosphate, which may be responsible for its effectiveness in treating IBD. Imipramine N-oxide hydrate also has an effect on liver cells, which may lead to its effectiveness in treating infectious diseases. The drug is not active against autoimmune diseases, but it may have an effect on toll-like receptors.

Formula: C₁₉H₂₄N₂O·xH₂O

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 296.41 g/mol

Ref: 3D-FI24562