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CAS 68291-97-4

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Zonisamide

Description:
Zonisamide is an anticonvulsant medication primarily used in the treatment of epilepsy and, in some cases, for weight management. It is classified as a sulfonamide and exhibits a unique chemical structure that includes a benzisoxazole moiety. The substance is known for its ability to inhibit voltage-gated sodium channels and reduce the release of excitatory neurotransmitters, which contributes to its anticonvulsant properties. Zonisamide is typically administered orally and is characterized by its relatively long half-life, allowing for once-daily dosing in many patients. It is generally well-tolerated, although some side effects may include dizziness, fatigue, and gastrointestinal disturbances. Additionally, zonisamide has been noted for its potential to induce metabolic acidosis in some individuals. As with any medication, it is essential for patients to discuss their medical history and any potential interactions with healthcare providers before starting treatment. Overall, zonisamide represents a valuable option in the management of seizure disorders.
Formula:C8H8N2O3S
InChI:InChI=1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12)
InChI key:InChIKey=UBQNRHZMVUUOMG-UHFFFAOYSA-N
SMILES:C(S(N)(=O)=O)C=1C=2C(ON1)=CC=CC2
Synonyms:
  • CI 912
  • AD 810
  • 3-(Sulfamoylmethyl)-1,2-benzisoxazole
  • 1,2-Benzisoxazole-3-methanesulfonamide
  • Zonisamide
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