CAS 68302-57-8

Amlexanox

Description:

Amlexanox is a chemical compound primarily recognized for its role as an anti-inflammatory and anti-allergic agent. It is classified as a small molecule and is often utilized in the treatment of conditions such as aphthous ulcers and allergic rhinitis. The substance exhibits a unique mechanism of action, which involves the inhibition of certain inflammatory pathways, thereby reducing symptoms associated with these conditions. Amlexanox is typically administered topically or orally, depending on the specific application. Its chemical structure includes a fused ring system, contributing to its biological activity. The compound is generally well-tolerated, although, like any medication, it may have potential side effects. In terms of solubility, Amlexanox is known to have moderate solubility in organic solvents, which can influence its formulation in pharmaceutical preparations. Overall, Amlexanox represents a valuable therapeutic option in managing specific inflammatory and allergic responses.

Formula: C₁₆H₁₄N₂O₄

InChI: InChI=1S/C16H14N2O4/c1-7(2)8-3-4-12-9(5-8)13(19)10-6-11(16(20)21)14(17)18-15(10)22-12/h3-7H,1-2H3,(H2,17,18)(H,20,21)

InChI key: InChIKey=SGRYPYWGNKJSDL-UHFFFAOYSA-N

SMILES: O=C1C=2C(OC=3C1=CC(C(C)C)=CC3)=NC(N)=C(C(O)=O)C2

Synonyms:

• 2-Amino-5-oxo-7-propan-2-ylchromeno[2,3-b]pyridine-3-carboxylic acid
• 2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid
• 2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylicAcid
• 2-Amino-7-isopropyl-1-azaxanthone-3-carboxylic Acid
• 2-Amino-7-isopropyl-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic Acid
• 2-Amino-7-isopropyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid
• 2-Amino-7-isopropyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylicacid
• 2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid
• 2-amino-7-(1-methylethyl)-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid
• 5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid, 2-amino-7-(1-methylethyl)-5-oxo-
• Aa 673
• Amoxanox
• Aphthasol
• Aphtheal
• Chx 3673
• Elics
• Solfa

Amlexanox

CAS: 68302-57-8

Formula: C₁₆H₁₄N₂O₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 298.30

Ref: 3B-A2401

2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid

CAS: 68302-57-8

Formula: C₁₆H₁₄N₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 298.2934

Ref: IN-DA00333Z

Amlexanox

CAS: 68302-57-8

Amlexanox (AA673) treats ulcers by blocking leukotrienes, histamine, reducing inflammation, pain, and healing time.

Formula: C₁₆H₁₄N₂O₄

Purity: 99.67% - ≥95%

Color and Shape: White Crystalline Solid

Molecular weight: 298.29

Ref: TM-T1639

Amlexanox

CAS: 68302-57-8

Formula: C₁₆H₁₄N₂O₄

Purity: ≥ 99.0%

Color and Shape: White to off-white powder

Molecular weight: 298.29

Ref: 7W-GP9065

2-Amino-7-Isopropyl-5-Oxo-5H-Chromeno[2,3-b]Pyridine-3-Carboxylic Acid

CAS: 68302-57-8

2-Amino-7-Isopropyl-5-Oxo-5H-Chromeno[2,3-b]Pyridine-3-Carboxylic Acid

Purity: 98%

Molecular weight: 298.29g/mol

Ref: 54-OR1010290

Amlexanox

CAS: 68302-57-8

Amlexanox

Purity: ≥95%

Molecular weight: 298.29g/mol

Ref: 54-BUP16960

Amlexanox RS

CAS: 68302-57-8

Color and Shape: White

Ref: 2K-1012000021

Amlexanox

Controlled Product

CAS: 68302-57-8

Applications Inhibits release of allergic mediators from mast cells. Antiallergic; antiasthmatic. Amlexanox, used to treat asthma and mouth sores in humans, may also be a promising treatment for type 2 diabetes and obesity (Nat. Med., DOI: 10.1038/nm.3082).
References Rankov, G., et al.: Ophthalmic Res., 22, 359 (1990), Greer, R.O., et al.: J. Oral Mxillofac. Surg., 51, 243 (1993); Chem. and Eng. News p. 43, Feb. 18, 2013

Formula: C₁₆H₁₄N₂O₄

Color and Shape: Neat

Molecular weight: 298.29

Ref: TR-A633410

Amlexanox

CAS: 68302-57-8

Amlexanox inhibits serine/threonine-protein kinase TBK1 and IKK-ε enzyme. It is an antiallergic and anti-inflammatory drug that has been shown to be effective in treating rhinitis and allergic asthma in clinical studies. It prevents the slow-reacting substance of anaphylaxis (SRS-A) from being released chemically as a mediator and may have antagonistic effects on interleukin-3.

Formula: C₁₆H₁₄N₂O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 298.29 g/mol

Ref: 3D-FA17873

Amlexanox - Bio-X ™

CAS: 68302-57-8

Amlexanox is an antiallergic and anti-inflammatory drug that has been shown to be effective in treating rhinitis and allergic asthma in clinical studies. It prevents the slow-reacting substance of anaphylaxis (SRS-A) from being released chemically as a mediator and may have antagonistic effects on interleukin-3.

Formula: C₁₆H₁₄N₂O₄

Purity: (%) Min. 99%

Color and Shape: Powder

Molecular weight: 298.29 g/mol

Ref: 3D-BA164161

2-Amino-7-isopropyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid

CAS: 68302-57-8

Formula: C₁₆H₁₄N₂O₄

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 298.298

Ref: 10-F093426