CAS 68367-52-2

Sorbinil

Description:

Sorbinil, with the CAS number 68367-52-2, is a synthetic compound primarily recognized for its role as an aldose reductase inhibitor. This characteristic makes it significant in the context of diabetes management, as it can help mitigate complications associated with diabetic neuropathy and retinopathy by preventing the conversion of glucose to sorbitol. Sorbinil is typically presented as a white to off-white crystalline powder, exhibiting low solubility in water but higher solubility in organic solvents. Its molecular structure includes a hydroxyl group and an amine, contributing to its biological activity. Sorbinil has been studied for its potential therapeutic effects, although its clinical use may be limited due to side effects or availability of alternative treatments. As with many pharmacological agents, understanding its pharmacokinetics, mechanism of action, and safety profile is crucial for its application in medical settings. Overall, Sorbinil represents an important compound in the field of medicinal chemistry, particularly in the context of managing diabetes-related complications.

Formula: C₁₁H₉FN₂O₃

InChI: InChI=1S/C11H9FN2O3/c12-6-1-2-8-7(5-6)11(3-4-17-8)9(15)13-10(16)14-11/h1-2,5H,3-4H2,(H2,13,14,15,16)/t11-/m0/s1

InChI key: InChIKey=LXANPKRCLVQAOG-NSHDSACASA-N

SMILES: O=C1[C@]2(C=3C(OCC2)=CC=C(F)C3)NC(=O)N1

Synonyms:

• (+)-(4S)-6-Fluorospiro[chroman-4,4′-imidazolidine]-2′,5′-dione
• (4S)-6-Fluoro-2,3-dihydrospiro[4H-1-benzopyran-4,4′-imidazolidine]-2′,5′-dione
• (4S)-6-fluoro-2,3-dihydro-2'H,5'H-spiro[chromene-4,4'-imidazolidine]-2',5'-dione
• (S)-(+)-Sorbinil
• (S)-6-Fluorospiro(chroman-4,4'-imidazolidine)-2',5'-dione
• 6-fluoro-2,3-dihydro-2'H,5'H-spiro[chromene-4,4'-imidazolidine]-2',5'-dione
• Cp 45,634
• Nsc 355082
• Sorbinil [USAN:INN:BAN]
• Sorbinilo
• Sorbinilo [Spanish]
• Sorbinilum
• Sorbinilum [Latin]
• Spiro(4H-1-benzopyran-4,4'-imidazolidine)-2',5'-dione, 6-fluoro-2,3-dihydro-, (S)-
• Spiro[4H-1-benzopyran-4,4′-imidazolidine]-2′,5′-dione, 6-fluoro-2,3-dihydro-, (4S)-
• Spiro[4H-1-benzopyran-4,4′-imidazolidine]-2′,5′-dione, 6-fluoro-2,3-dihydro-, (S)-
• Unii-G4186B906P

Sorbinil

CAS: 68367-52-2

Sorbinil

Purity: ≥98%

Molecular weight: 236.2g/mol

Ref: 54-BUP05307

Sorbinil

CAS: 68367-52-2

Formula: C₁₁H₉FN₂O₃

Molecular weight: 236.20

Ref: 7W-GL5053

Sorbinil

CAS: 68367-52-2

Sorbinil is an Aldose reductase inhibitor.

Formula: C₁₁H₉FN₂O₃

Purity: 99.85%

Color and Shape: Solid

Molecular weight: 236.2

Ref: TM-T16910