CAS 683808-78-8

Poloppin

CAS: 683808-78-8

Poloppin is a chemical compound that inhibits the activity of plk1, an enzyme that plays an important role in cell division. Poloppin binds to the ATP binding site of plk1 and blocks its function by preventing ATP from binding. It has been shown to inhibit mitotic checkpoint and cellular proliferation in cancer cells. This compound also induces apoptotic cell death through biochemical signaling pathways.

Formula: C₂₀H₁₅BrF₃NO₂

Purity: Min. 95%

Molecular weight: 438.2 g/mol

Ref: 3D-ICB80878

Poloppin

CAS: 683808-78-8

Poloppin modulates polo-like kinases, targets mutant KRAS, and enhances Crizotinib's effects against KRAS-mutant cancers.

Formula: C₂₀H₁₅BrF₃NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 438.24

Ref: TM-T24652