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CAS 68399-80-4

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3-[Bis(2-hydroxyethyl)amino]-2-hydroxypropanesulfonic acid

Description:
3-[Bis(2-hydroxyethyl)amino]-2-hydroxypropanesulfonic acid, commonly known as BES, is a zwitterionic buffer widely used in biological and biochemical research. It features a sulfonic acid group, which imparts strong acidity, and two hydroxyethyl groups that enhance its solubility in aqueous solutions. BES is characterized by its ability to maintain a stable pH in biological systems, making it particularly useful in cell culture and enzyme assays. The compound is typically stable across a range of temperatures and pH levels, although it is sensitive to extreme conditions. Its buffering capacity is effective in the physiological pH range, which is crucial for many biochemical reactions. Additionally, BES is non-toxic to cells, making it an ideal choice for experiments involving live cells. Its compatibility with various biological molecules further enhances its utility in laboratory settings. Overall, BES is valued for its effectiveness as a buffer and its minimal interference with biological processes.
Formula:C7H17NO6S
InChI:InChI=1S/C7H17NO6S/c9-3-1-8(2-4-10)5-7(11)6-15(12,13)14/h7,9-11H,1-6H2,(H,12,13,14)
InChI key:InChIKey=XCBLFURAFHFFJF-UHFFFAOYSA-N
SMILES:N(CC(CS(=O)(=O)O)O)(CCO)CCO
Synonyms:
  • (2R)-3-[bis(2-hydroxyethyl)ammonio]-2-hydroxypropane-1-sulfonate
  • (2S)-3-[bis(2-hydroxyethyl)ammonio]-2-hydroxypropane-1-sulfonate
  • 1-Propanesulfonic acid, 3-[bis(2-hydroxyethyl)amino]-2-hydroxy-
  • 3-[Bis(2-Hydroxyethyl)Amino]-2-Hydroxypropane-1-Sulfonic Acid
  • 3-[Bis(2-hydroxyethyl)amino]-2-hydroxy-1-propanesulfonic acid
  • 3-[Bis(2-hydroxyethyl)amino]-2-hydroxypropanesulfonic acid
  • 3-[N,N-Bis(2-hydroxyethyl)amino]-2-hydroxy-1-propanesulfonic acid
  • Dipso
  • N,N-Bis(2-hydroxyethyl)-3-amino-2-hydroxypropanosulfonic acid
  • NSC 378145
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