CAS 68401-82-1

Ceftizoxime sodium

Description:

Ceftizoxime sodium is a broad-spectrum cephalosporin antibiotic, primarily used for the treatment of various bacterial infections. It is effective against both Gram-positive and Gram-negative bacteria, making it a valuable option in clinical settings. The compound is characterized by its stability against certain beta-lactamases, which are enzymes produced by some bacteria to resist antibiotic action. Ceftizoxime sodium is typically administered via injection, as it is not well absorbed when taken orally. Its mechanism of action involves inhibiting bacterial cell wall synthesis, leading to cell lysis and death. The substance is generally well-tolerated, though potential side effects may include allergic reactions, gastrointestinal disturbances, and alterations in blood coagulation. It is important to use this antibiotic judiciously to minimize the risk of developing antibiotic resistance. As with all antibiotics, susceptibility testing is recommended to ensure effectiveness against the specific bacterial strain being treated.

Formula: C₁₃H₁₃N₅O₅S₂·Na

InChI: InChI=1S/C13H13N5O5S2.Na/c1-23-17-7(5-4-25-13(14)15-5)9(19)16-8-10(20)18-6(12(21)22)2-3-24-11(8)18;/h2,4,8,11H,3H2,1H3,(H2,14,15)(H,16,19)(H,21,22);/b17-7-;/t8-,11-;/m1./s1

InChI key: InChIKey=LNJZODVQDGCASS-LIGXYSTNSA-N

SMILES: O=C1N2[C@@]([C@@H]1NC(/C(=N\OC)/C3=CSC(N)=N3)=O)(SCC=C2C(O)=O)[H].[Na]

Synonyms:

• (6R,7R)-7-[[(2Z)-(2-Amino-4-Thiazolyl)(Methoxyimino)Acetyl]Amino]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid Sodium Salt
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-, monosodium salt, [6R-[6α,7β(Z)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-, monosodium salt, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-, sodium salt (1:1), (6R,7R)-
• 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)-1-oxoethyl]amino]-8-oxo-, sodium salt, (6R,7R)- (1:1)
• Cefizox
• Ceftix
• Ceftizon
• Ceftizoxime sodium salt
• Eposerin
• Fk 749
• Fr 13479
• Skf 88373
• Sodium 7-[2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-cephem-4-carboxylate
• sodium (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Ceftizoxime sodium

CAS: 68401-82-1

Formula: C₁₃H₁₂N₅NaO₅S₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 405.3846

Ref: IN-DA00JKHS

Ceftizoxime Sodium

CAS: 68401-82-1

Ceftizoxime Sodium

Purity: 97%

Molecular weight: 461.38g/mol

Ref: 54-OR1029982

Ceftizoxime sodium salt

CAS: 68401-82-1

Formula: C₁₃H₁₂N₅NaO₅S₂

Purity: 850 - 995 μg/mg (anhydrous basis)

Color and Shape: White to light-yellow crystalline powder

Molecular weight: 405.38

Ref: 7W-GA1247

Ceftizoxime Sodium

CAS: 68401-82-1

Ceftizoxime, a 3rd-gen cephalosporin, targets PBPs in Gram-positive/negative bacteria, like cefotaxime, but not metabolized.

Formula: C₁₃H₁₂N₅NaO₅S₂

Color and Shape: White To Light Yellow Crystalline Powder

Molecular weight: 405.38

Ref: TM-T21386

Ceftizoxime Sodium Salt (Mixture of Diastereomers)

Controlled Product

CAS: 102044-69-9, 68401-82-1

Formula: C₁₃H₁₂N₅O₅S₂·Na

Color and Shape: Neat

Molecular weight: 405.38

Ref: TR-C244770

Ceftizoxime sodium

CAS: 68401-82-1

Ceftizoxime sodium is a sodium salt form of ceftizoxime with similar action and applications as ceftizoxime.

Formula: C₁₃H₁₂N₅NaO₅S₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 405.39 g/mol

Ref: 3D-FC40872