CAS 68436-47-5

Isowighteone

Description:

Isowighteone, identified by the CAS number 68436-47-5, is a chemical substance that falls within the category of ketones. It is characterized by its unique molecular structure, which typically includes a carbonyl group (C=O) flanked by hydrocarbon chains. This compound is often utilized in various industrial applications, including as a solvent or in the formulation of fragrances and flavoring agents due to its pleasant odor profile. Isowighteone is known for its moderate volatility and solubility in organic solvents, making it suitable for use in formulations that require a balance of evaporation rate and stability. Additionally, it may exhibit properties such as low toxicity and environmental persistence, which are important considerations in its handling and application. As with many chemical substances, safety data sheets should be consulted for specific handling guidelines and potential hazards associated with Isowighteone. Overall, its chemical characteristics make it a versatile compound in both industrial and commercial settings.

Formula: C₂₀H₁₈O₅

InChI: InChI=1S/C20H18O5/c1-11(2)3-4-13-7-12(5-6-16(13)22)15-10-25-18-9-14(21)8-17(23)19(18)20(15)24/h3,5-10,21-23H,4H2,1-2H3

InChI key: InChIKey=SWDSVBNAMCDHTF-UHFFFAOYSA-N

SMILES: O=C1C=2C(=CC(O)=CC2O)OC=C1C3=CC(CC=C(C)C)=C(O)C=C3

Synonyms:

• 5,7-Dihydroxy-3-[4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-4H-1-benzopyran-4-one
• 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-[4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-
• Isowighteone
• 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-[4-hydroxy-3-(3-methyl-2-butenyl)phenyl]-
• 3′-Dimethylallylgenistein

5,7-Dihydroxy-3-(4-hydroxy-3-(3-methylbut-2-en-1-yl)phenyl)-4H-chromen-4-one

CAS: 68436-47-5

Formula: C₂₀H₁₈O₅

Purity: 94.0%

Color and Shape: Solid

Molecular weight: 338.3539

Ref: IN-DA00FEPX

Isowighteone

CAS: 68436-47-5

Isowighteone (3'-Prenylgenistein) is an isoflavonoid compound isolated from the hairy roots of Mucuna pruriens with anticancer activity.

Formula: C₂₀H₁₈O₅

Color and Shape: Solid

Molecular weight: 338.35

Ref: TM-TN5445

Isowighteone

Controlled Product

CAS: 68436-47-5

Applications Isowighteone is a natural product derivative of Genistein (G350000). Genistein exhibits specific inhibitory activity against tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol.
References Akiyama, T., et al.: J. Biol. Chem., 262, 5592 (1987); O'Dell, T.J., et al.: Nature, 353, 588 (1991); Aharonovits, O., et al.: Biochim Biophys. Acta, 1112, 181 (1992); Platanias, L.C., et al.: J. Biol. Chem., 267, 24053 (1992); Yoshida, H., et al.: Biochim. Biophys. Acta, 1137, 321 (1992); Uckun, F.M., et al.: Science, 267, 886 (1995); Merck Index 12th ed. 4395, Huang, R.Q.; Fang, M.J.; Dillon, G.H., Mol. Brain Res. 67: 177-183 (1999)

Formula: C₂₀H₁₈O₅

Color and Shape: Neat

Molecular weight: 338.354

Ref: TR-I918230

Isowighteone

CAS: 68436-47-5

Isowighteone is a naturally occurring flavonoid, which is derived from various plant sources, particularly in traditional medicinal herbs. Its biological activity stems from its structure, characterized by phenolic hydroxyl groups that enable it to participate in redox reactions, highlighting its antioxidant properties.

Formula: C₂₀H₁₈O₅

Purity: Min. 95%

Molecular weight: 338.35 g/mol

Ref: 3D-FI138625