CAS 68475-42-3: Anagrelide

Description: Anagrelide is a synthetic compound primarily used as a medication to reduce elevated platelet counts in conditions such as essential thrombocythemia. It functions as a selective inhibitor of megakaryocyte differentiation and platelet production, thereby decreasing the risk of thrombotic events associated with high platelet levels. The chemical structure of Anagrelide includes a pyrimidinone core, which contributes to its pharmacological activity. It is typically administered orally and is metabolized in the liver, with its effects being dose-dependent. Common side effects may include headache, dizziness, and gastrointestinal disturbances. Anagrelide's mechanism of action involves the inhibition of cyclic adenosine monophosphate (cAMP) phosphodiesterase, leading to increased cAMP levels, which in turn affects platelet production. Due to its specific action on megakaryocytes, Anagrelide is distinct from other antiplatelet agents, making it a valuable option in managing certain hematological disorders. As with any medication, it is essential to monitor patients for potential adverse effects and interactions with other drugs.

Formula: C₁₀H₇Cl₂N₃O

InChI: InChI=1S/C10H7Cl2N3O/c11-6-1-2-7-5(9(6)12)3-15-4-8(16)14-10(15)13-7/h1-2H,3-4H2,(H,13,14,16)

InChI key: InChIKey=OTBXOEAOVRKTNQ-UHFFFAOYSA-N

SMILES: O=C1N=C2NC3=CC=C(Cl)C(Cl)=C3CN2C1

Synonyms:

• 11-6-1
• 6,7-Dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2(3H)-one
• 6,7-Dichloro-5,10-dihydroimidazo[2,1-b]quinazolin-2(3H)-one
• 68475-42-3
• Bl 4162A
• Xagrid
• imidazo[2,1-b]quinazolin-2(3H)-one, 6,7-dichloro-1,5-dihydro-
• imidazo[2,1-b]quinazolin-2(3H)-one, 6,7-dichloro-5,10-dihydro-
• Anagrelide

6,7-dichloro-5,10-dihydro-3H-imidazo[2,1-b]quinazolin-2-one

CAS: 68475-42-3

• Formula: C₁₀H₇Cl₂N₃O
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 256.0881

Anagrelide

CAS: 68475-42-3

• Purity: ≥98%
• Molecular weight: 256.09g/mol

Anagrelide

CAS: 68475-42-3

• Formula: C₁₀H₇Cl₂N₃O
• Molecular weight: 256.09

Anagrelide-13C3

CAS: 68475-42-3

• Formula: C₇₁₃C₃H₇Cl₂N₃O
• Color and Shape: White To Off-White Solid
• Molecular weight: 259.06

Anagrelide

CAS: 68475-42-3

Anagrelide (Xagrid) is a Platelet-reducing Agent.

• Formula: C₁₀H₇Cl₂N₃O
• Purity: 100%
• Color and Shape: Solid
• Molecular weight: 256.09

Anagrelide

CAS: 68475-42-3

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• Formula: C₁₀H₇Cl₂N₃O
• Purity: Min. 95%
• Color and Shape: White/Off-White Solid
• Molecular weight: 256.09 g/mol