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CAS 68550-75-4

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Cilostamide

Description:
Cilostamide is a chemical compound primarily recognized for its role as a phosphodiesterase inhibitor, specifically targeting phosphodiesterase type 3 (PDE3). This inhibition leads to increased levels of cyclic adenosine monophosphate (cAMP) within cells, which can enhance vasodilation and improve blood flow. Cilostamide is often studied for its potential therapeutic applications in cardiovascular diseases, particularly in conditions like intermittent claudication and heart failure. The compound is characterized by its moderate solubility in organic solvents and relatively low solubility in water, which can influence its bioavailability and pharmacokinetics. Additionally, cilostamide exhibits a specific molecular structure that contributes to its biological activity, including a unique arrangement of functional groups that facilitate its interaction with target enzymes. As with many pharmacological agents, the safety profile, side effects, and interactions with other medications are important considerations in its clinical use. Overall, cilostamide represents a significant area of research in the development of treatments for vascular-related conditions.
Formula:C20H26N2O3
InChI:InChI=1S/C20H26N2O3/c1-22(16-6-3-2-4-7-16)20(24)8-5-13-25-17-10-11-18-15(14-17)9-12-19(23)21-18/h9-12,14,16H,2-8,13H2,1H3,(H,21,23)
InChI key:InChIKey=UIAYVIIHMORPSJ-UHFFFAOYSA-N
SMILES:O(CCCC(N(C)C1CCCCC1)=O)C=2C=C3C(=CC2)NC(=O)C=C3
Synonyms:
  • Butanamide, N-cyclohexyl-4-((1,2-dihydro-2-oxo-6-quinolinyl)oxy)-N-methyl-
  • Cilostamida
  • Cilostamida [INN-Spanish]
  • Cilostamide [INN]
  • Cilostamidum
  • Cilostamidum [INN-Latin]
  • N-Cyclohexyl-4-((1,2-dihydro-2-oxo-6-quinolyl)oxy)-N-methylbutyramide
  • N-Cyclohexyl-4-[(1,2-dihydro-2-oxo-6-quinolinyl)oxy]-N-methylbutanamide
  • N-cyclohexyl-N-methyl-4-[(2-oxo-1,2-dihydroquinolin-6-yl)oxy]butanamide
  • Opc 3689
  • See more synonyms
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