CAS 68550-75-4

Cilostamide

Description:

Cilostamide is a chemical compound primarily recognized for its role as a phosphodiesterase inhibitor, specifically targeting phosphodiesterase type 3 (PDE3). This inhibition leads to increased levels of cyclic adenosine monophosphate (cAMP) within cells, which can enhance vasodilation and improve blood flow. Cilostamide is often studied for its potential therapeutic applications in cardiovascular diseases, particularly in conditions like intermittent claudication and heart failure. The compound is characterized by its moderate solubility in organic solvents and relatively low solubility in water, which can influence its bioavailability and pharmacokinetics. Additionally, cilostamide exhibits a specific molecular structure that contributes to its biological activity, including a unique arrangement of functional groups that facilitate its interaction with target enzymes. As with many pharmacological agents, the safety profile, side effects, and interactions with other medications are important considerations in its clinical use. Overall, cilostamide represents a significant area of research in the development of treatments for vascular-related conditions.

Formula: C₂₀H₂₆N₂O₃

InChI: InChI=1S/C20H26N2O3/c1-22(16-6-3-2-4-7-16)20(24)8-5-13-25-17-10-11-18-15(14-17)9-12-19(23)21-18/h9-12,14,16H,2-8,13H2,1H3,(H,21,23)

InChI key: InChIKey=UIAYVIIHMORPSJ-UHFFFAOYSA-N

SMILES: O(CCCC(N(C)C1CCCCC1)=O)C=2C=C3C(=CC2)NC(=O)C=C3

Synonyms:

• Butanamide, N-cyclohexyl-4-((1,2-dihydro-2-oxo-6-quinolinyl)oxy)-N-methyl-
• Cilostamida
• Cilostamida [INN-Spanish]
• Cilostamide [INN]
• Cilostamidum
• Cilostamidum [INN-Latin]
• N-Cyclohexyl-4-((1,2-dihydro-2-oxo-6-quinolyl)oxy)-N-methylbutyramide
• N-Cyclohexyl-4-[(1,2-dihydro-2-oxo-6-quinolinyl)oxy]-N-methylbutanamide
• N-cyclohexyl-N-methyl-4-[(2-oxo-1,2-dihydroquinolin-6-yl)oxy]butanamide
• Opc 3689
• Opc 3869
• Unii-45S5605Q18

Cilostamide

CAS: 68550-75-4

A cell-permeable selective inhibitor of cGMP-inhibited phosphodiesterase

Formula: C₂₀H₂₆N₂O₃

Molecular weight: 342.43

Ref: 02-J65319

N-Cyclohexyl-N-methyl-4-(1,2-dihydro-2-oxo-6-quinolyloxy)butyramide

CAS: 68550-75-4

Formula: C₂₀H₂₆N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 342.4320

Ref: IN-DA0034LX

Cilostamide

CAS: 68550-75-4

Cilostamide

Purity: ≥95%

Molecular weight: 342.43g/mol

Ref: 54-BUP05815

Cilostamide phosphodiesterase inhibitor

CAS: 68550-75-4

Formula: C₂₀H₂₆N₂O₃

Molecular weight: 342.43

Ref: 7W-GL5139

Cilostamide

CAS: 68550-75-4

Cilostamide (OPC3689) is a selective phosphodiesterase (PDE)3A and PDE3B inhibitor(IC50 values of 27 and 50 nM, respectively)

Formula: C₂₀H₂₆N₂O₃

Purity: 98.87%

Color and Shape: White To Off-White Solid

Molecular weight: 342.43

Ref: TM-T7642