CAS 68550-75-4: Cilostamide

Description: Cilostamide is a chemical compound primarily recognized for its role as a phosphodiesterase inhibitor, specifically targeting phosphodiesterase type 3 (PDE3). This inhibition leads to increased levels of cyclic adenosine monophosphate (cAMP) within cells, which can enhance vasodilation and improve blood flow. Cilostamide is often studied for its potential therapeutic applications in cardiovascular diseases, particularly in conditions like intermittent claudication and heart failure. The compound is characterized by its moderate solubility in organic solvents and relatively low solubility in water, which can influence its bioavailability and pharmacokinetics. Additionally, cilostamide exhibits a specific molecular structure that contributes to its biological activity, including a unique arrangement of functional groups that facilitate its interaction with target enzymes. As with many pharmacological agents, the safety profile, side effects, and interactions with other medications are important considerations in its clinical use. Overall, cilostamide represents a significant area of research in the development of treatments for vascular-related conditions.

Formula: C₂₀H₂₆N₂O₃

InChI: InChI=1S/C20H26N2O3/c1-22(16-6-3-2-4-7-16)20(24)8-5-13-25-17-10-11-18-15(14-17)9-12-19(23)21-18/h9-12,14,16H,2-8,13H2,1H3,(H,21,23)

InChI key: InChIKey=UIAYVIIHMORPSJ-UHFFFAOYSA-N

SMILES: O=C1C=CC=2C=C(OCCCC(=O)N(C)C3CCCCC3)C=CC2N1

Synonyms:

• Butanamide, N-cyclohexyl-4-((1,2-dihydro-2-oxo-6-quinolinyl)oxy)-N-methyl-
• Cilostamida
• Cilostamida [INN-Spanish]
• Cilostamide [INN]
• Cilostamidum
• Cilostamidum [INN-Latin]
• N-Cyclohexyl-4-((1,2-dihydro-2-oxo-6-quinolyl)oxy)-N-methylbutyramide
• N-Cyclohexyl-4-[(1,2-dihydro-2-oxo-6-quinolinyl)oxy]-N-methylbutanamide
• N-cyclohexyl-N-methyl-4-[(2-oxo-1,2-dihydroquinolin-6-yl)oxy]butanamide
• Opc 3689
• Opc 3869
• Unii-45S5605Q18
• Cilostamide

Cilostamide

CAS: 68550-75-4

A cell-permeable selective inhibitor of cGMP-inhibited phosphodiesterase This Thermo Scientific Chemicals brand product was originally …

• Formula: C₂₀H₂₆N₂O₃
• Molecular weight: 342.43

N-Cyclohexyl-N-methyl-4-(1,2-dihydro-2-oxo-6-quinolyloxy)butyramide

CAS: 68550-75-4

• Formula: C₂₀H₂₆N₂O₃
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 342.432

Cilostamide

CAS: 68550-75-4

• Purity: 98%
• Molecular weight: 342.43g/mol

Cilostamide phosphodiesterase inhibitor

CAS: 68550-75-4

• Formula: C₂₀H₂₆N₂O₃
• Molecular weight: 342.43

Cilostamide

CAS: 68550-75-4

Cilostamide (OPC3689) is a selective phosphodiesterase (PDE)3A and PDE3B inhibitor(IC50 values of 27 and 50 …

• Formula: C₂₀H₂₆N₂O₃
• Purity: 98.87%
• Color and Shape: White To Off-White Solid
• Molecular weight: 342.43

Cilostamide

CAS: 68550-75-4

Cilostamide is a drug that inhibits the phosphodiesterase type 3 (PDE3) enzyme, which is responsible …

• Formula: C₂₀H₂₆N₂O₃
• Purity: Min. 95%
• Molecular weight: 342.43 g/mol