CAS 686-50-0

L-Leucylglycine

Description:

L-Leucylglycine is a dipeptide composed of the amino acids leucine and glycine, linked by a peptide bond. It is classified as a non-essential amino acid derivative, meaning it can be synthesized by the body. The substance is typically white to off-white in appearance and is soluble in water, which makes it useful in various biochemical applications. L-Leucylglycine exhibits characteristics common to peptides, such as the ability to participate in hydrogen bonding and forming secondary structures. It plays a role in protein synthesis and can influence metabolic processes. Additionally, it may have applications in pharmaceuticals and nutrition, particularly in formulations aimed at muscle recovery and growth due to the presence of leucine, which is known for its role in stimulating protein synthesis. The compound's stability and reactivity can be influenced by factors such as pH and temperature, which are important considerations in its handling and storage. Overall, L-Leucylglycine is a significant compound in biochemistry and nutrition.

Formula: C₈H₁₆N₂O₃

InChI: InChI=1S/C8H16N2O3/c1-5(2)3-6(9)8(13)10-4-7(11)12/h5-6H,3-4,9H2,1-2H3,(H,10,13)(H,11,12)/t6-/m0/s1

InChI key: InChIKey=LESXFEZIFXFIQR-LURJTMIESA-N

SMILES: [C@@H](C(NCC(O)=O)=O)(CC(C)C)N

Synonyms:

• (S)-2-(2-Amino-4-methylpentamido)acetic acid
• 101: PN: EP2161028 PAGE: 10 claimed protein
• 10: PN: WO2011159938 SEQID: 76 claimed protein
• 1374: PN: EP2071334 SEQID: 1452 claimed protein
• 1374: PN: WO2009077864 SEQID: 1452 claimed protein
• 147: PN: US20130123467 SEQID: 176 claimed protein
• 2-[(2S)-2-Amino-4-methylpentanamido]acetic acid
• 2-[[(2S)-2-Amino-4-methylpentanoyl]amino]acetic acid
• 202: PN: WO2011032181 SEQID: 222 unclaimed protein
• 210: PN: WO2009114815 SEQID: 222 unclaimed protein
• 35: PN: WO0028996 SEQID: 4 unclaimed protein
• 436: PN: WO2005081628 SEQID: 438 claimed protein
• <span class="text-smallcaps">L</span>-Leucylglycine
• Glycine, <span class="text-smallcaps">L</span>-leucyl-
• Glycine, N-<span class="text-smallcaps">L</span>-leucyl-
• H-Leu-Gly-OH
• L-Leucyl-glycine
• Leu-Gly hydrate
• Morphine tolerance peptide
• Glycine, N-L-leucyl-
• Glycine, L-leucyl-

L-Leucylglycine

CAS: 686-50-0

Formula: C₈H₁₆N₂O₃

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 188.23

Ref: 3B-L0032

H-Leu-Gly-OH

CAS: 686-50-0

The dipeptide Leu-Gly inhibits the ubiquitin-mediated proteolysis.

Formula: C₈H₁₆N₂O₃

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 188.23

Ref: 01-4000131

H-Leu-Gly-OH

CAS: 686-50-0

Formula: C₈H₁₆N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 188.2242

Ref: IN-DA005OY1

H-Leu-Gly-OH

CAS: 686-50-0

H-Leu-Gly-OH

Purity: 98%

Molecular weight: 188.22g/mol

Ref: 54-OR1032136

(S)-2-(2-Amino-4-methylpentanamido)acetic acid

CAS: 686-50-0

Formula: C₈H₁₆N₂O₃

Purity: 98%

Molecular weight: 188.227

Ref: 10-F224551

Leu-Gly • ½ H2O

CAS: 686-50-0

Leu-Gly is a cyclic peptide that is composed of the amino acid sequence Leu-Gly. It has antimicrobial, anti-inflammatory, and immunomodulatory properties. This peptide exhibits calcium binding, which may be due to its structural analysis with trifluoroacetic acid in human serum. A model system using coli K-12 cells was used to study the biological properties of Leu-Gly. The locomotor activity of these cells was inhibited by Leu-Gly, which may be due to its ability to bind with cyclic adenosine monophosphate (cAMP) receptors on the cell surface.
LEU Gly is a member of the class of antimicrobial peptides that are important for fighting infections. It has been shown to have strong activity against E. coli K12 and various strains of Staphylococcus aureus isolated from humans with autoimmune diseases.

Formula: C₈H₁₆N₂O₃H₂O

Purity: Min. 95%

Molecular weight: 197.23 g/mol

Ref: 3D-OLG-3024