CAS 6863-73-6

2-Amino-3-chloropyrazine

Description:

2-Amino-3-chloropyrazine is a heterocyclic organic compound characterized by its pyrazine ring, which contains two nitrogen atoms in the 1 and 4 positions. This compound features an amino group (-NH2) at the 2-position and a chlorine atom at the 3-position of the pyrazine ring. It is typically a colorless to light yellow solid, soluble in polar solvents such as water and alcohols, and exhibits moderate stability under standard conditions. The presence of both the amino and chloro substituents contributes to its reactivity, making it a useful intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its molecular structure allows for various chemical reactions, including nucleophilic substitutions and coupling reactions. Additionally, 2-amino-3-chloropyrazine may exhibit biological activity, which can be explored for potential applications in medicinal chemistry. As with many nitrogen-containing heterocycles, it is important to handle this compound with care, considering its potential toxicity and environmental impact.

Formula: C₄H₄ClN₃

InChI: InChI=1/C4H4ClN3/c5-3-4(6)8-2-1-7-3/h1-2H,(H2,6,8)

SMILES: c1cnc(c(Cl)n1)N

Synonyms:

• 2-Pyrazinamine, 3-chloro-
• 3-Chloro-2-pyrazinamine
• 3-Chloropyrazin-2-amine

2-Amino-3-chloropyrazine

CAS: 6863-73-6

2-Amino-3-chloropyrazine

Formula: C₄H₄ClN₃

Purity: 97%

Color and Shape: white crystals

Molecular weight: 129.55g/mol

Ref: 54-OR6127

2-Amino-3-chloropyrazine

CAS: 6863-73-6

Formula: C₄H₄ClN₃

Purity: >98.0%(GC)

Color and Shape: White to Light yellow to Dark green powder to crystal

Molecular weight: 129.55

Ref: 3B-A2143

2-Amino-3-chloropyrazine

CAS: 6863-73-6

2-Amino-3-chloropyrazine is an active analogue of pyrazinamide, which is a potent antimycobacterial drug. It has been shown to have bacteriostatic activity against Mycobacterium tuberculosis in vitro and in vivo. 2-Amino-3-chloropyrazine has been shown to inhibit mitochondrial membrane potential, which may be due to its ability to inhibit hepg2 cell growth by decreasing intracellular ATP levels. It also inhibits the synthesis of bacterial DNA and protein, thereby inhibiting bacterial growth. 2-Amino-3-chloropyrazine has also been shown to have antitumor properties against mouse tumor cells. The pharmacokinetic properties of this drug are not well understood yet, but it has been shown that it can be detected in serum after administration

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 129.55 g/mol

Ref: 3D-FA02773

2-Amino-3-chloropyrazine

CAS: 6863-73-6

Formula: C₄H₄ClN₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 129.55

Ref: 10-F035839