CAS 68630-75-1

buserelin acetate

Description:

Buserelin acetate is a synthetic peptide analog of gonadotropin-releasing hormone (GnRH), primarily used in medical applications related to hormone regulation. It functions as a potent agonist of GnRH, stimulating the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland. This action can lead to a temporary increase in sex hormone levels, which is utilized in various therapeutic contexts, including the treatment of hormone-sensitive cancers and certain reproductive disorders. Buserelin acetate is typically administered via injection and is characterized by its stability and prolonged action compared to natural GnRH. The substance is soluble in water and exhibits a specific molecular structure that contributes to its biological activity. As with many peptide-based drugs, its use may be associated with side effects, and its administration should be carefully monitored by healthcare professionals. Overall, buserelin acetate plays a significant role in endocrinology and reproductive medicine.

Formula: C₆₂H₉₀N₁₆O₁₅

InChI: InChI=1/C60H86N16O13.C2H4O2/c1-7-64-57(87)48-15-11-23-76(48)58(88)41(14-10-22-65-59(61)62)69-51(81)42(24-33(2)3)70-56(86)47(31-89-60(4,5)6)75-52(82)43(25-34-16-18-37(78)19-17-34)71-55(85)46(30-77)74-53(83)44(26-35-28-66-39-13-9-8-12-38(35)39)72-54(84)45(27-36-29-63-32-67-36)73-50(80)40-20-21-49(79)68-40;1-2(3)4/h8-9,12-13,16-19,28-29,32-33,40-48,66,77-78H,7,10-11,14-15,20-27,30-31H2,1-6H3,(H,63,67)(H,64,87)(H,68,79)(H,69,81)(H,70,86)(H,71,85)(H,72,84)(H,73,80)(H,74,83)(H,75,82)(H4,61,62,65);1H3,(H,3,4)/t40-,41-,42-,43-,44-,45-,46-,47+,48-;/m0./s1

Synonyms:

• Buserelin acetate [USAN:JAN]
• 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-O-tert-butyl-D-seryl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide monoacetate (salt)
• Hoe 766 Mp
• Hoe 766Mp
• Luteinizing hormone-releasing factor (pig), 6-(O-(1,1-dimethylethyl)-D-serine)-9-(N-ethyl-L-prolinamide)-10-deglycinamide-, monoacetate (salt)
• Receptal
• Suprefact
• 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-O-tert-butyl-D-seryl-L-leucyl-N~5~-(diaminomethylidene)-L-ornithyl-N-ethyl-L-prolinamide acetate (1:1)
• Buserelin acetate

BUSERELIN CRS

CAS: 68630-75-1

BUSERELIN CRS

Ref: 41-B1168000

BUSERELIN FOR NMR IDENTIFICATION CRS

CAS: 68630-75-1

BUSERELIN FOR NMR IDENTIFICATION CRS

Formula: C₆₀H₈₆N₁₆O₁₃

Color and Shape: Added Modified

Molecular weight: 1239.424

Ref: 41-Y0001814

BUSERELIN FOR PEAK IDENTIFICATION CRS

CAS: 68630-75-1

BUSERELIN FOR PEAK IDENTIFICATION CRS

Formula: C₆₀H₈₆N₁₆O₁₃

Color and Shape: White. Whitish. Powder.

Molecular weight: 1239.424

Ref: 41-Y0001740

Buserelin Acetate

CAS: 68630-75-1

Buserelin Acetate

Purity: ≥98%

Molecular weight: 1299.48g/mol

Ref: 54-BUP02081

Buserelin acetate salt

CAS: 68630-75-1

Formula: C₆₀H₈₆N₁₆O₁₃·C₂H₄O₂

Purity: ≥ 95.0%

Color and Shape: White or off-white powder

Molecular weight: 1299.48

Ref: 7W-GL9726

Buserelin Acetate (57982-77-1 free base)

CAS: 68630-75-1

Buserelin Acetate (57982-77-1 free base) (Buserelin Acetate) is an agonist of gonadotropin-releasing hormone receptor(GnRHR).

Formula: C₆₂H₉₀N₁₆O₁₅

Purity: 99.31% - 99.78%

Color and Shape: Solid

Molecular weight: 1299.48

Ref: TM-TP1307

Buserelin Acetate

CAS: 68630-75-1

Stability Hygroscopic
Applications Gondadotropin-releasing hormone agonist, used to treat hormone-responsive cancers such as prostate and breast cancer. Synthetic nonapeptide agonist analog of LH-RH. Antineolpastic (hormonal).
References Lam, P., et al.: Gynecol. Endocrinol., 24, 674 (2008), Chi, K., et al.: J. Urol., 180, 565 (2008), Menchaca, A., et al.: Theriogenol., 72, 477 (2009), Harada, T., et al.: Fertility and Sterility, 91, 675 (2009),

Formula: C₆₀H₈₆N₁₆O₁₃·C₂H₄O₂

Color and Shape: Neat

Molecular weight: 1299.48

Ref: TR-B689740

Buserelin acetate

Controlled Product

CAS: 68630-75-1

Agonist of hypothalamic neuropeptide LHRH

Formula: C₆₂H₉₀N₁₆O₁₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 1,299.48 g/mol

Ref: 3D-FP19363