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CAS 68676-88-0

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Trichostatin C

Description:
Trichostatin C is a natural compound classified as a histone deacetylase (HDAC) inhibitor, which plays a significant role in the regulation of gene expression. It is derived from the fermentation of certain fungi, particularly from the genus *Streptomyces*. The compound is known for its ability to induce hyperacetylation of histones, leading to alterations in chromatin structure and enhanced transcriptional activity of various genes. Trichostatin C exhibits a broad spectrum of biological activities, including potential anti-cancer properties, as it can influence cell cycle progression and apoptosis in cancer cells. Additionally, it has been studied for its effects on neurodegenerative diseases and other conditions where HDAC activity is implicated. The molecular structure of Trichostatin C includes a complex arrangement of carbon, hydrogen, oxygen, and nitrogen atoms, contributing to its biological activity. Due to its potent effects, Trichostatin C is often used in research settings to explore epigenetic regulation and therapeutic applications in various diseases.
Formula:C23H32N2O8
InChI:InChI=1S/C23H32N2O8/c1-13(11-14(2)19(28)15-6-8-16(9-7-15)25(3)4)5-10-18(27)24-33-23-22(31)21(30)20(29)17(12-26)32-23/h5-11,14,17,20-23,26,29-31H,12H2,1-4H3,(H,24,27)/b10-5+,13-11+/t14-,17-,20-,21+,22-,23+/m1/s1
InChI key:InChIKey=YECWTLGLNDDPGE-PIFXLSLCSA-N
SMILES:O(NC(/C=C/C(=C/[C@H](C(=O)C1=CC=C(N(C)C)C=C1)C)/C)=O)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O
Synonyms:
  • Trichostatin C
  • (2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-N-(β-D-glucopyranosyloxy)-4,6-dimethyl-7-oxo-2,4-heptadienamide
  • 2,4-Heptadienamide, 7-[4-(dimethylamino)phenyl]-N-(β-D-glucopyranosyloxy)-4,6-dimethyl-7-oxo-, (2E,4E,6R)-
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