CAS 68682-01-9

2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one

Description:

2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one, also known by its CAS number 68682-01-9, is a flavonoid compound characterized by its complex polyphenolic structure. This compound features multiple hydroxyl groups, which contribute to its potential antioxidant properties. The presence of a benzopyran moiety indicates that it belongs to the flavonoid class, which is known for various biological activities, including anti-inflammatory and anticancer effects. The 3-methyl-2-buten-1-yl side chain enhances its lipophilicity, potentially influencing its bioavailability and interaction with biological membranes. Its structural features suggest that it may exhibit significant interactions with cellular pathways, making it of interest in pharmacological research. Additionally, the compound's solubility and stability can vary depending on environmental conditions, which is crucial for its application in medicinal chemistry and natural product research. Overall, this compound represents a fascinating area of study within the field of natural products and their therapeutic potentials.

Formula: C₂₀H₂₀O₅

Synonyms:

• (2R/S)-6-PNG
• 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
• 6PNG
• Naringenin 6-Prenyl Racemate

5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-(3-methylbut-2-en-1-yl)chroman-4-one

CAS: 68682-01-9

5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-(3-methylbut-2-en-1-yl)chroman-4-one

Purity: 98%

Molecular weight: 340.38g/mol

Ref: 54-OR1074842

6-prenylnaringenin

CAS: 68682-01-9

Oxygen-heterocyclic compound

Formula: C₂₀H₂₀O₅

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 340.38

Ref: 5G-80520

6-Prenyl-rac-naringenin

CAS: 68682-01-9

Applications 6-Prenyl-rac-naringenin is a natural product isolated from Cudrania tricuspidata root which showed growth inhibition against Escherichia coli, Staphylococcus aureus and Klebsiella pneumoniae.
References Alzand, K., et al.: World. J. Pharm. Res., 3, 981-997 (2014)

Formula: C₂₀H₂₀O₅

Color and Shape: Neat

Molecular weight: 340.37

Ref: TR-P712905

(2R/S)-6-PNG

CAS: 68682-01-9

(2R/S)-6-PNG is a voltage-gated sodium channel blocker that has been shown to be neuroprotective in animal models of neuropathic pain. It binds to the neuron's membrane with high affinity and specificity, blocking the influx of sodium ions and thereby reducing neuronal excitability. The compound is able to block the voltage-gated sodium channels at low concentrations (1 μM) without affecting other ion channels. (2R/S)-6-PNG has been shown to be a potent inhibitor of neuropathic pain in an animal model of sciatic nerve injury. This compound also blocks voltage-gated sodium channels on sensory neurons, which may be responsible for its analgesic effects. In addition, this compound has been shown to have ligation properties that do not penetrate the cell membrane and affect only the intracellular domain of NaV1.8 channels.

Formula: C₂₀H₂₀O₅

Purity: Min. 95%

Molecular weight: 340.37 g/mol

Ref: 3D-TCA68201

(2R/S)-6-PNG

CAS: 68682-01-9

(2R/S)-6-PNG (6-Prenylnaringenin) from hops is a natural histone deacetylase inhibitor that blocks T-type calcium channels reducing neurogenicity in mice.

Formula: C₂₀H₂₀O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 340.37

Ref: TM-T37427