CAS 6870-67-3

(15S,20R)-12-hydroxy-15,20-dihydro-15,20-epoxysenecionan-11,16-dione

Description:

The chemical substance known as "(15S,20R)-12-hydroxy-15,20-dihydro-15,20-epoxysenecionan-11,16-dione," with the CAS number 6870-67-3, is a naturally occurring compound that belongs to the class of sesquiterpenoids. This compound is characterized by its complex bicyclic structure, which includes multiple functional groups such as hydroxyl and epoxide moieties, contributing to its reactivity and biological activity. The stereochemistry indicated by the (15S,20R) configuration suggests specific spatial arrangements of atoms, which can significantly influence the compound's interactions with biological systems. Sesquiterpenoids are often noted for their diverse range of pharmacological properties, including anti-inflammatory and antimicrobial activities. The presence of the dione functional groups in this compound may also suggest potential reactivity in various chemical reactions, making it of interest in both synthetic and medicinal chemistry. Overall, this compound exemplifies the intricate relationship between molecular structure and biological function in natural products.

Formula: C₁₈H₂₅NO₆

InChI: InChI=1S/C18H25NO6/c1-10-8-18(11(2)25-18)16(21)24-13-5-7-19-6-4-12(14(13)19)9-23-15(20)17(10,3)22/h4,10-11,13-14,22H,5-9H2,1-3H3/t10-,11+,13-,14-,17-,18+/m1/s1

InChI key: InChIKey=IAPHXJRHXBQDQJ-WKMWQDDRSA-N

SMILES: C[C@H]1[C@]2(O1)C(=O)O[C@]3([C@@]4(N(CC3)CC=C4COC(=O)[C@](C)(O)[C@H](C)C2)[H])[H]

Synonyms:

• Spiro[[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-3(2H),2′-oxirane]-2,7(4H)-dione, 5,6,9,11,13,14,14a,14b-octahydro-6-hydroxy-3′,5,6-trimethyl-, [3S-[3R*(R*),5S*,6S*,14aS*,14bS*]]-
• (2′S,3′S,5R,6R,14aR,14bR)-5,6,9,11,13,14,14a,14b-Octahydro-6-hydroxy-3′,5,6-trimethylspiro[[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-3(2H),2′-oxirane]-2,7(4H)-dione
• Jacobine
• Senecionan-11,16-dione, 15,20-epoxy-15,20-dihydro-12-hydroxy-, (15α,20S)-
• Spiro[[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-3(2H),2′-oxirane]-2,7(4H)-dione, 5,6,9,11,13,14,14a,14b-octahydro-6-hydroxy-3′,5,6-trimethyl-, (2′S,3′S,5R,6R,14aR,14bR)-
• (15R,20S)-15,20-Dihydro-15,20-epoxy-12-hydroxysenecionan-11,16-dione
• (20S)-15α,20-Epoxy-15,20-dihydro-12-hydroxysenecionan-11,16-dione
• Spiro[[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-3(2H),2'-oxirane]-2,7(4H)-dione, 5,6,9,11,13,14,14a,14b-octahydro-6-hydroxy-3',5,6-trimethyl-, (2'S,3'S,5R,6R,14aR,14bR)-
• NSC-89936

Jacobine

CAS: 6870-67-3

Jacobine causes dose-dependent DNA interstrand cross-links, catalyzed by guinea pig liver enzymes in vitro.

Formula: C₁₈H₂₅NO₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 351.39

Ref: TM-TN4345

Jacobine

CAS: 6870-67-3

Formula: C₁₈H₂₅NO₆

Molecular weight: 351.40

Ref: 4Z-J-005001

Jacobine-d3

CAS: 6870-67-3

Formula: C₁₈H₂₂D₃NO₆

Molecular weight: 354.42

Ref: 4Z-J-005002

Jacobine

CAS: 6870-67-3

Natural alkaloid

Formula: C₁₈H₂₅NO₆

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 351.39

Ref: 5G-83434

Jacobine

CAS: 6870-67-3

Formula: C₁₈H₂₅NO₆

Color and Shape: Neat

Molecular weight: 351.394

Ref: TR-J210395

Jacobine

CAS: 6870-67-3

Jacobine is a naturally occurring compound that is extracted from specific medicinal plants known for their therapeutic properties. As an alkaloid, Jacobine functions by interacting with cellular pathways to exert its effects. Its primary mode of action involves modulation of neurotransmitter activity, which can influence pain signaling pathways, providing relief from various types of pain.

Formula: C₁₈H₂₅NO₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 351.39 g/mol

Ref: 3D-BJ161539