CAS 6870-94-6

(6α,11β)-11,17-Dihydroxy-6-methylpregna-1,4-diene-3,20-dione

Description:

The chemical substance known as (6α,11β)-11,17-Dihydroxy-6-methylpregna-1,4-diene-3,20-dione, with the CAS number 6870-94-6, is a synthetic steroid that belongs to the class of corticosteroids. It exhibits anti-inflammatory and immunosuppressive properties, making it useful in various therapeutic applications, particularly in the treatment of inflammatory and autoimmune conditions. The structure of this compound features a pregnane backbone, characterized by a steroid nucleus with multiple hydroxyl groups that contribute to its biological activity. The presence of double bonds in the steroid structure enhances its potency and efficacy. This compound is often studied for its pharmacological effects and potential side effects, which can include alterations in metabolism and immune response. As with many corticosteroids, careful consideration of dosage and duration of use is essential to minimize adverse effects. Overall, this compound exemplifies the complexity and utility of synthetic steroids in medical science.

Formula: C₂₂H₃₀O₄

InChI: InChI=1S/C22H30O4/c1-12-9-15-16-6-8-22(26,13(2)23)21(16,4)11-18(25)19(15)20(3)7-5-14(24)10-17(12)20/h5,7,10,12,15-16,18-19,25-26H,6,8-9,11H2,1-4H3/t12-,15-,16-,18-,19+,20-,21-,22-/m0/s1

InChI key: InChIKey=UWMKPWKZGHRUQC-RSWUNGFYSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C([C@@H](C)C3)=CC(=O)C=C4)([C@@H](O)C1)[H])[H])(CC[C@@]2(C(C)=O)O)[H]

Synonyms:

• (6α,11β)-11,17-Dihydroxy-6-methylpregna-1,4-diene-3,20-dione
• 11β,17α-Dihydroxy-6α-methylpregna-1,4-diene-3,20-dione
• NSC 125051
• Pregna-1,4-diene-3,20-dione, 11β,17-dihydroxy-6α-methyl-
• Pregna-1,4-diene-3,20-dione,11,17-dihydroxy-6-methyl-, (6a,11b)-
• Methylprednisolone Intermediates

Deltamedrane

CAS: 6870-94-6

Deltamedrane

Color and Shape: Beige

Ref: 47-572

Fluorometholone Related Compound A (11β,17α-Dihydroxy-6α-methylpregna-1,4-diene-3,20-dione)

CAS: 6870-94-6

Ketone-alcohols and ketone-aldehydes, nesoi

Formula: C₂₂H₃₀O₄

Color and Shape: White Off-White Powder

Molecular weight: 358.21441

Ref: 45-1278018

Pregna-1,4-diene-3,20-dione,11,17-dihydroxy-6-methyl-, (6a,11b)-

CAS: 6870-94-6

Formula: C₂₂H₃₀O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 358.4712

Ref: IN-DA006HCW

Methylprednisolone EP Impurity L (Fluorometholone USP Related Compound A)

CAS: 6870-94-6

Formula: C₂₂H₃₀O₄

Color and Shape: White To Off-White Solid

Molecular weight: 358.48

Ref: 4Z-P-11148

Deltamedrane

CAS: 6870-94-6

Stability Hygroscopic
Applications Deltamedrane is an impurity in the synthesis of Fluorometholone (F593145), a glucocorticoid; anti-inflammatory.
References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982); Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984);

Formula: C₂₂H₃₀O₄

Color and Shape: Beige

Molecular weight: 358.47

Ref: TR-D230695

Deltamedrane

Controlled Product

CAS: 6870-94-6

Deltamedrane is a hydroxylated steroid that is classified as an electron vector. It has been shown to inhibit the expression of proteins in mammalian cells by binding to their DNA. Deltamedrane can be used as an agent for gene therapy, and has also been shown to act as a chaperone for the transfer of heterologous nucleic acid. Deltamedrane binds to the hydroxylase proteins, which are responsible for hydroxylating proteins and hormones. Hydroxylation is required for the production of protein and hormone chains, and it also regulates their activity.

Formula: C₂₂H₃₀O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 358.47 g/mol

Ref: 3D-GAA87094

Methylprednisolone EP Impurity L

CAS: 6870-94-6

Formula: C₂₂H₃₀O₄

Molecular weight: 358.5

Ref: ST-EA-CP-M14056