CAS 6873-13-8

(-)-Phellodendrine

Description:

(-)-Phellodendrine is an alkaloid primarily derived from the bark of the Phellodendron amurense tree, commonly known as Amur cork tree. This compound is characterized by its chiral structure, exhibiting optical activity due to the presence of a stereocenter. It typically appears as a white to pale yellow crystalline solid and has a molecular formula that reflects its complex structure. (-)-Phellodendrine is known for its potential pharmacological properties, including anti-inflammatory, analgesic, and antimicrobial effects, making it of interest in medicinal chemistry and natural product research. Its mechanism of action may involve modulation of various biological pathways, although further studies are often required to fully elucidate these effects. Additionally, it is important to handle this compound with care, as with many alkaloids, due to its biological activity and potential toxicity at higher concentrations. Overall, (-)-Phellodendrine represents a significant compound in the study of natural products and their applications in health and medicine.

Formula: C₂₀H₂₄NO₄

InChI: InChI=1S/C20H23NO4/c1-21-5-4-12-8-19(24-2)18(23)10-15(12)16(21)6-13-7-17(22)20(25-3)9-14(13)11-21/h7-10,16H,4-6,11H2,1-3H3,(H-,22,23)/p+1/t16-,21-/m0/s1

InChI key: InChIKey=RBBVPNQTBKHOEQ-KKSFZXQISA-O

SMILES: C[N@+]12[C@](C=3C(CC1)=CC(OC)=C(O)C3)(CC=4C(C2)=CC(OC)=C(O)C4)[H]

Synonyms:

• (7S,13aS)-2,11-dihydroxy-3,10-dimethoxy-7-methyl-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinolinium
• (7S,13aS)-5,8,13,13a-Tetrahydro-2,11-dihydroxy-3,10-dimethoxy-7-methyl-6H-dibenzo[a,g]quinolizinium
• 13aα-Berbinium, 2,11-dihydroxy-3,10-dimethoxy-7-methyl-
• 6H-Dibenzo(a,g)quinolizinium, 5,8,13,13a-tetrahydro-2,11-dihydroxy-3,10-dimethoxy-7-methyl-, (7S-cis)-
• 6H-Dibenzo[a,g]quinolizinium, 5,8,13,13a-tetrahydro-2,11-dihydroxy-3,10-dimethoxy-7-methyl-, (7S,13aS)-
• N-Methylcoreximine
• OB-5 Compound
• Phallodendrin
• Phellodendrine

Phellodendrine

CAS: 6873-13-8

Formula: C₂₀H₂₄NO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 342.4089

Ref: IN-DA00FAFR

Phellodendrine

CAS: 6873-13-8

Formula: C₂₀H₂₄NO₄

Molecular weight: 342.41

Ref: 7W-GY9396

Phellodendrine

CAS: 6873-13-8

Phellodendrine

Purity: ≥98%

Molecular weight: 342.41g/mol

Ref: 54-BUP00047

Phellodendrine

CAS: 6873-13-8

Formula: C₂₀H₂₄NO₄

Purity: 95%~99%

Molecular weight: 342.414

Ref: BP-BP1083

Phellodendrine

CAS: 6873-13-8

Phellodendrine may treat nephritis by blocking macrophage and T cell activity in glomeruli.

Formula: C₂₀H₂₄NO₄

Purity: 98.7% - 99.94%

Color and Shape: Solid

Molecular weight: 342.41

Ref: TM-T6S0781

Phellodendrine

CAS: 6873-13-8

Phellodendrine is a glycol ester of berberine that has been used in traditional Chinese medicine for the treatment of hepatitis. Phellodendrine has been shown to activate toll-like receptor 4 (TLR4) and inhibit il-2 receptor expression in human monocytes and neutrophils, leading to an inhibited production of inflammatory cytokines such as IL-2. Phellodendrine also displays anti-cancer and anti-inflammatory activities, which may be due to its ability to inhibit mitochondrial membrane potential and regulate sodium citrate levels. The biological properties of phellodendrine have been determined using surface methodology coupled with analytical methods. The analyzed compounds are detected by liquid chromatography–mass spectrometry/mass spectrometry (LC-MS/MS).

Formula: C₂₀H₂₄NO₄

Purity: Min. 97 Area-%

Color and Shape: Powder

Molecular weight: 342.41 g/mol

Ref: 3D-FP73850