CAS 68813-55-8

oxantel pamoate

Description:

Oxantel pamoate is an anthelmintic agent primarily used in the treatment of intestinal parasitic infections, particularly those caused by nematodes. It is a derivative of oxantel, which is effective against various helminths, including Ascaris lumbricoides and Trichuris trichiura. The compound is characterized by its ability to disrupt the energy metabolism of parasites, leading to their paralysis and subsequent expulsion from the host. Oxantel pamoate is typically administered orally and is known for its relatively low toxicity in humans, making it a preferred choice in certain therapeutic regimens. The substance is often combined with other anthelmintics to enhance efficacy and broaden the spectrum of activity against different parasitic infections. In terms of physical properties, oxantel pamoate is a white to off-white powder, and it is generally stable under normal storage conditions. Its solubility profile indicates limited solubility in water, which can influence its bioavailability and absorption in the gastrointestinal tract. Overall, oxantel pamoate plays a significant role in public health, particularly in regions where soil-transmitted helminth infections are prevalent.

Formula: C₄₉H₄₈N₄O₈

InChI: InChI=1/C23H16O6.C13H16N2O/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;1-15-9-3-8-14-13(15)7-6-11-4-2-5-12(16)10-11/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2,4-7,10,16H,3,8-9H2,1H3/b;7-6+

InChI key: InChIKey=CCOAINFUFGBHBA-UETGHTDLSA-N

SMILES: C(=C/C1=CC(O)=CC=C1)\C=2N(C)CCCN2.C(C=1C2=C(C=C(C(O)=O)C1O)C=CC=C2)C=3C4=C(C=C(C(O)=O)C3O)C=CC=C4

Synonyms:

• (E)-m-(2-(1,4,5,6-Tetrahydro-1-methyl-2-pyrimidinyl)vinyl)phenol 4,4'-methylenebis(3-hydroxy-2-naphthoate) (1:1) (salt)
• 1-Methyl-2-[3-Hydroxyphenylethenyl]-1,4,5,6-Tetrahydropyrimidine Compound With 4,4'-Methylenebis[3-Hydroxy-2-Naphthoic Acid]
• 2-Naphthalenecarboxylic acid, 4,4′-methylenebis[3-hydroxy-, compd. with (E)-3-[2-(1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)ethenyl]phenol (1:1)
• 2-Naphthalenecarboxylic acid, 4,4′-methylenebis[3-hydroxy-, compd. with 3-[(1E)-2-(1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)ethenyl]phenol (1:1)
• 4,4'-Methylenebis(3-hydroxy-2-naphthoic) acid, compound with (E)-3-(2-(1,4,5,6-tetrahydro-1-methylpyrimidin-2-yl)vinyl)phenol (1:1)
• 4,4'-methanediylbis(3-hydroxynaphthalene-2-carboxylic acid) - 3-[(E)-2-(1-methyl-1,4,5,6-tetrahydropyrimidin-2-yl)ethenyl]phenol (1:1)
• Cp 14,445-16
• Oxanel pamoate
• Oxantel ebonate
• Oxantel embonate
• Phenol, 3-(2-(1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)ethenyl), (E)-, 4,4'-methylenebis(3-hydroxy-2-naphthalenecarboxylate) (1:1) (salt)
• Phenol, 3-[(1E)-2-(1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)ethenyl]-, 4,4′-methylenebis[3-hydroxy-2-naphthalenecarboxylate] (1:1) (salt)
• Telopar
• Unii-Upy1D732T0
• Oxantel pamoate
• 2-Naphthalenecarboxylic acid, 4,4-methylenebis3-hydroxy-, compd. with 3-(1E)-2-(1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)ethenylphenol (1:1)
• 4,4'-Methylenebis[3-hydroxy-2-naphthalenecarboxylic Acid 3-[(1E)-2-(1,4,5,6-Tetrahydro-1-Methyl-2-pyriMidinyl)ethenyl]phenol
• Parasite,inhibit,Inhibitor,Oxantel Pamoate,Oxantel
• Octahydronaphthol
• Einecs 272-332-6
• (E)-3-[2-(1,4,5,6-Tetrahydro-1-Methyl-2-pyriMidinyl)ethenyl]phenol 4,4'-Methylenebis[3-hydroxy-2-naphthalenecarboxylate] Salt

Oxantel (pamoate)

CAS: 68813-55-8

Formula: C₃₆H₃₂N₂O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 604.6485

Ref: IN-DA01DPYQ

Oxantel Pamoate

CAS: 68813-55-8

Oxantel Pamoate (Oxantel embonate) is used as an Antinematodal agent.

Formula: C₃₆H₃₂N₂O₇

Purity: 99% - 99.89%

Color and Shape: Solid

Molecular weight: 604.65

Ref: TM-T0323

Oxantel Pamoate

CAS: 68813-55-8

Oxantel Pamoate

Purity: ≥98%

Molecular weight: 604.65g/mol

Ref: 54-BUP17703

Oxantel pamoate

CAS: 68813-55-8

Formula: C₁₃H₁₆N₂O·C₂₃H₁₆O₆

Molecular weight: 604.65

Ref: 7W-GA6137

Oxantel Pamoate

CAS: 68813-55-8

Formula: C₂₃H₁₆O₆·C₁₃H₁₆N₂O

Color and Shape: White To Off-White Solid

Molecular weight: 388.38 216.29

Ref: 4Z-O-171

Oxantel Pamoate

Controlled Product

CAS: 68813-55-8

Formula: C₂₃H₁₆O₆·C₁₃H₁₆N₂O

Color and Shape: Neat

Molecular weight: 604.65

Ref: 86-MM0893.00

Oxantel Pamoate

CAS: 68813-55-8

Applications Oxantel Pamoate is used as an anthelmintic drug.
References Reitzer, L., et al.: J. Biol. Chem., 1979, 254, 2669 (1979), Huber, R., et al.: J. Neurosci. Res., 75, 441 (2004), Kim, J., et al.: Cell Metab. 3, 177 (2006), Bonnet, S., et al.: Cancer Cell., 11, 37 (2007),

Formula: C₂₃H₁₆O₆·C₁₃H₁₆N₂O

Color and Shape: Light Yellow Solid

Molecular weight: 604.65

Ref: TR-O845250