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CAS 68865-60-1

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PEG dithiol

Description:
PEG dithiol, or polyethylene glycol dithiol, is a bifunctional compound characterized by the presence of two thiol (-SH) groups attached to a polyethylene glycol (PEG) backbone. This structure imparts unique properties, making PEG dithiol a versatile reagent in various applications, particularly in bioconjugation and materials science. It is typically a colorless, viscous liquid or solid, depending on its molecular weight. The thiol groups enable it to participate in thiol-ene and thiol-disulfide exchange reactions, facilitating the formation of cross-linked networks or conjugates with proteins, peptides, and other biomolecules. PEG dithiol is also known for its hydrophilicity, which enhances solubility in aqueous environments, making it suitable for biomedical applications, including drug delivery and tissue engineering. Additionally, its non-toxic and biocompatible nature makes it an attractive choice for use in various formulations. Overall, PEG dithiol serves as a crucial building block in the development of innovative materials and therapeutic strategies.
Formula:(C2H4O)nC4H10OS2
InChI:InChI=1S/C6H14O2S2/c9-5-3-7-1-2-8-4-6-10/h9-10H,1-6H2
InChI key:InChIKey=HCZMHWVFVZAHCR-UHFFFAOYSA-N
SMILES:C(COCCS)OCCS
Synonyms:
  • Poly(oxy-1,2-ethanediyl), α-(2-mercaptoethyl)-ω-(2-mercaptoethoxy)-
  • Polyethylene glycol bis(2-mercaptoethyl)ether
  • PEG dithiol
  • Polyethylene glycol dithiol
  • α,ω-Bis(mercapto)poly(oxy-1,2-ethanediyl)
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