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CAS 68892-41-1

:

5′-O-[Bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-N-(2-methyl-1-oxopropyl)guanosine

Description:
5′-O-[Bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-N-(2-methyl-1-oxopropyl)guanosine, with the CAS number 68892-41-1, is a synthetic nucleoside derivative that exhibits unique structural characteristics due to the presence of a modified guanosine backbone. This compound features a 5′-O-substituent that includes a bis(4-methoxyphenyl)phenylmethyl group, which enhances its lipophilicity and potentially its biological activity. The 2′-deoxy configuration indicates that it lacks a hydroxyl group at the 2′ position, which is typical of DNA nucleosides, thus influencing its stability and interaction with nucleic acids. The N-(2-methyl-1-oxopropyl) modification at the guanine base may affect its binding affinity and specificity towards nucleic acid targets. Overall, this compound is of interest in medicinal chemistry and molecular biology for its potential applications in drug development and as a tool for studying nucleic acid interactions. Its unique structural features may also contribute to its pharmacological properties, making it a subject of research in the field of nucleoside analogs.
Formula:C35H37N5O7
InChI:InChI=1S/C35H37N5O7/c1-21(2)32(42)38-34-37-31-30(33(43)39-34)36-20-40(31)29-18-27(41)28(47-29)19-46-35(22-8-6-5-7-9-22,23-10-14-25(44-3)15-11-23)24-12-16-26(45-4)17-13-24/h5-17,20-21,27-29,41H,18-19H2,1-4H3,(H2,37,38,39,42,43)/t27-,28+,29+/m0/s1
InChI key:InChIKey=RMQXDNUKLIDXOS-ZGIBFIJWSA-N
SMILES:C(OC[C@H]1O[C@H](C[C@@H]1O)N2C3=C(N=C2)C(=O)N=C(NC(C(C)C)=O)N3)(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6
Synonyms:
  • 5'-O-Dimethoxytrityl-N-Isobutyryl-Deoxyguanosine
  • 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-N-isobutyrylguanosine
  • 5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-N-(2-methylpropanoyl)guanosine
  • 5-O-(4,4-Dimethoxytrityl)-N2-Isobutyryl-2-Deoxyguanosine
  • 5′-O-(Dimethoxytrityl)-N-isobutyryldeoxyguanosine
  • 5′-O-[Bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-N-(2-methyl-1-oxopropyl)guanosine
  • 68892-41-1
  • Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-N-(2-methyl-1-oxopropyl)-
  • N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine
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