CAS 68892-42-2

N(2)-isobutyroyl-2'-deoxyguanosine

Description:

N(2)-isobutyroyl-2'-deoxyguanosine is a modified nucleoside that features a guanine base linked to a deoxyribose sugar, with an isobutyroyl group attached at the N(2) position of the guanine. This modification can influence the molecule's biological activity, stability, and interactions with other biomolecules. The presence of the isobutyroyl group may enhance lipophilicity, potentially affecting cellular uptake and pharmacokinetics. As a nucleoside analog, it may also play a role in research related to nucleic acid metabolism, antiviral therapies, or cancer treatment, as modified nucleosides are often investigated for their ability to interfere with nucleic acid synthesis or function. The compound's CAS number, 68892-42-2, allows for its identification in chemical databases and literature. Overall, N(2)-isobutyroyl-2'-deoxyguanosine represents a significant area of interest in medicinal chemistry and molecular biology due to its structural modifications and potential therapeutic applications.

Formula: C₁₄H₁₉N₅O₅

Synonyms:

• N2-Isobutyryl-2-deoxyguanosine (dG-iBu)
• Ibu-Deoxyguanosine
• dG-Ibu
• N2-Isobutyryl-2'-deoxyguanosine
• Guanosine, 2'-deoxy-N-(2-methyl-1-oxopropyl)-
• N-Ib-Dg
• N2-Isobutyryldeoxyguanosine
• N2-Isobutyl-2'-Deoxyguanosine
• N2-Isobutyroyl-2'-Deoxyguanosine
• N2-(Ibu)-2'-Deoxyguanosine
• N2-(2-Methylpropanoyl)-2'Deoxy-Guanosine
• 2'-deoxy-N-(2-methylpropanoyl)guanosine

Guanosine, 2'-deoxy-N-(2-methyl-1-oxopropyl)-

CAS: 68892-42-2

Formula: C₁₄H₁₉N₅O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 337.3312

Ref: IN-DA00IBVP

2''-Deoxy-N2-isobutyrylguanosine

CAS: 68892-42-2

Ref: 7W-GN9941

N2-Isobutyryl-2'-deoxyguanosine

CAS: 68892-42-2

N2-Isobutyryl-2'-deoxyguanosine

Formula: C₁₄H₁₉N₅O₅

Purity: 98%

Color and Shape: white solid

Molecular weight: 337.33g/mol

Ref: 54-OR920104

N2-Isobutyryl-2'-deoxyguanosine

CAS: 68892-42-2

Formula: C₁₄H₁₉N₅O₅

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 337.34

Ref: 3B-I0700

N2-Isobutyryl-2-deoxyguanosine

CAS: 68892-42-2

N2-Isobutyryl-2-deoxyguanosine（iBu-dG） is a nucleoside analog that can be used to synthesize oligonucleotides.

Formula: C₁₄H₁₉N₅O₅

Purity: 97.03%

Color and Shape: Solid

Molecular weight: 337.33

Ref: TM-T66137

2'-Deoxy-N2-isobutyrylguanosine

CAS: 68892-42-2

2'-Deoxy-N2-isobutyrylguanosine (2'-DIBG) is an inhibitor of bacterial translocation that has been shown to inhibit the growth of several bacterial species. This drug binds to fatty acids, which are important for maintaining the integrity of the cell membrane and preventing bacterial translocation. 2'-DIBG also inhibits the production of reactive oxygen species by bacteria, which contributes to its antimicrobial activity. Inflammation can be reduced by inhibiting prostaglandin synthesis with 2'-DIBG. The inhibition of prostaglandin synthesis may be due to its ability to form acid conjugates with fatty acids and dicarboxylic acids, which are precursors for prostaglandins. 2'-DIBG also inhibits the synthesis of adenosine triphosphate (ATP) in bacteria, leading to a decrease in bacterial growth rate.

Formula: C₁₄H₁₉N₅O₅

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 337.34 g/mol

Ref: 3D-ND02989

N2-Isobutyryl-2′-deoxyguanosine

CAS: 68892-42-2

Formula: C₁₄H₁₉N₅O₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 337.336

Ref: 10-F434669