CAS 68902-57-8

Metioprim

Description:

Metioprim is a chemical compound primarily recognized for its application as an antibacterial agent, particularly in veterinary medicine. It is classified as a sulfonamide derivative, which means it shares structural similarities with sulfa drugs that inhibit bacterial growth by interfering with folic acid synthesis. Metioprim is often used in combination with other antimicrobial agents to enhance its efficacy against a broad spectrum of pathogens. The compound is characterized by its relatively low solubility in water, which can influence its bioavailability and pharmacokinetics. Additionally, Metioprim exhibits a moderate toxicity profile, necessitating careful dosage and administration in clinical settings. Its mechanism of action involves competitive inhibition of dihydropteroate synthase, an enzyme critical for bacterial survival. Overall, Metioprim's unique properties make it a valuable tool in the treatment of infections, particularly in animals, while ongoing research continues to explore its potential applications in human medicine.

Formula: C₁₄H₁₈N₄O₂S

InChI: InChI=1S/C14H18N4O2S/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15/h5-7H,4H2,1-3H3,(H4,15,16,17,18)

InChI key: InChIKey=HRZQMMXCASMDBP-UHFFFAOYSA-N

SMILES: C(C1=CC(OC)=C(SC)C(OC)=C1)C=2C(N)=NC(N)=NC2

Synonyms:

• Methioprim
• 2,4-Pyrimidinediamine, 5-[[3,5-dimethoxy-4-(methylthio)phenyl]methyl]-
• Metioprim
• 5-[[3,5-Dimethoxy-4-(methylthio)phenyl]methyl]-2,4-pyrimidinediamine
• Ro 12-6995

Metioprim

CAS: 68902-57-8

Metioprim is a competitive bacterial dihydrofolate reductases inhibitor.

Formula: C₁₄H₁₈N₄O₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 306.38

Ref: TM-T24459