CAS 68929-06-6

Uroporphyrin I dihydrochloride

Description:

Uroporphyrin I dihydrochloride is a chemical compound that belongs to the class of porphyrins, which are cyclic compounds characterized by their large, planar structures and ability to coordinate metal ions. This specific compound is a derivative of uroporphyrin, featuring a dihydrochloride form that indicates the presence of two hydrochloride ions associated with the uroporphyrin molecule. Uroporphyrin I is notable for its role in biological systems, particularly in the biosynthesis of heme, a vital component of hemoglobin and various enzymes. The compound exhibits strong absorption in the ultraviolet-visible spectrum, making it useful in photodynamic therapy and as a biological marker. Its solubility in water is enhanced by the presence of the hydrochloride groups, which also influence its stability and reactivity. Uroporphyrin I dihydrochloride can be utilized in research settings, particularly in studies related to porphyrin metabolism and related disorders. Safety data should be consulted for handling, as with any chemical substance, to ensure proper precautions are taken.

Formula: C₄₀H₄₀Cl₂N₄O₁₆

InChI: InChI=1/C40H38N4O16/c45-33(46)5-1-17-21(9-37(53)54)29-14-26-19(3-7-35(49)50)23(11-39(57)58)31(43-26)16-28-20(4-8-36(51)52)24(12-40(59)60)32(44-28)15-27-18(2-6-34(47)48)22(10-38(55)56)30(42-27)13-25(17)41-29/h13-16,41-42H,1-12H2,(H,45,46)(H,47,48)(H,49,50)(H,51,52)(H,53,54)(H,55,56)(H,57,58)(H,59,60)/b25-13u,26-14-,27-15-,28-16-,29-14u,30-13-,31-16u,32-15u

InChI key: InChIKey=DZLKLVAJOHLPKP-QXVOECHBSA-N

SMILES: C(CC(O)=O)C=1C(CC(O)=O)=C2NC1C=C3C(CC(O)=O)=C(CCC(O)=O)C(=N3)C=C4C(CC(O)=O)=C(CCC(O)=O)C(=CC5=NC(=C2)C(CCC(O)=O)=C5CC(O)=O)N4.Cl

Synonyms:

• 21H,23H-Porphine-2,7,12,17-tetrapropanoic acid, 3,8,13,18-tetrakis(carboxymethyl)-, dihydrochloride
• 21H,23H-Porphine-2,7,12,17-tetrapropanoic acid, 3,8,13,18-tetrakis(carboxymethyl)-, hydrochloride (1:2)
• 3,3',3'',3'''-[3,8,13,18-Tetrakis(Carboxymethyl)Porphyrin-2,7,12,17-Tetrayl]Tetrapropanoic Acid
• 3,8,13,18-Tetrakis(carboxymethyl)-21H,23H-porphine-2,7,12,17-tetrapropionic acid dihydrochloride
• Uroporphyrin I dihydrochloride
• Uroporphyrin I dihydrochloride
• UroporphyrinI2HCl
• UROPORPHYRIN I DIHYDROCHLORIDE 95+%
• DISCONTINUED
• 3-[7,12,17-tris(2-carboxyethyl)-3,8,13,18-tetrakis(carboxymethyl)-21,24-dihydroporphyrin-2-yl]propanoicacid,dihydrochloride
• 21h,23h-porphine-2,7,12,17-tetrapropanoicacid,3,8,13,18-tetrakis(carboxymethy

Uroporphyrin I dihydrochloride

CAS: 68929-06-6

Uroporphyrin I dihydrochloride is a facilitator of carbohydrate metabolism. It is a cofactor for the enzyme dehydrogenase and changes the optical properties of certain compounds. Uroporphyrin I dihydrochloride has been shown to modulate the redox potential in lung cells and inhibit human immunodeficiency virus (HIV) replication by inhibiting coproporphyrin production. This drug has also been shown to have an anticancer effect against both leukemia and colon cancer cell lines. Uroporphyrin I dihydrochloride reacts with oxygen, giving it a luminescent property that can be used to assay for its presence in biological systems.

Formula: C₄₀H₃₈N₄O₁₆•(HCl)₂

Purity: Min. 95%

Molecular weight: 903.67 g/mol

Ref: 3D-FU170853