CAS 6893-02-3

Triiodothyronine

Description:

Triiodothyronine, commonly referred to as T3, is a thyroid hormone that plays a crucial role in regulating metabolism, growth, and development in the body. It is synthesized from thyroxine (T4) and contains three iodine atoms, which are essential for its biological activity. T3 is a lipophilic molecule, allowing it to easily cross cell membranes and bind to nuclear receptors, influencing gene expression and metabolic processes. The hormone is primarily produced in the thyroid gland and is involved in various physiological functions, including the regulation of heart rate, body temperature, and energy expenditure. T3 is typically measured in clinical settings to assess thyroid function and diagnose disorders such as hypothyroidism or hyperthyroidism. Its chemical structure includes a phenolic ring and an amine group, contributing to its biological activity. Due to its potent effects, T3 is also used therapeutically in certain medical conditions, but its administration must be carefully monitored to avoid potential side effects associated with thyroid hormone imbalance.

Formula: C₁₅H₁₂I₃NO₄

InChI: InChI=1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1

InChI key: InChIKey=AUYYCJSJGJYCDS-LBPRGKRZSA-N

SMILES: O(C1=C(I)C=C(C[C@@H](C(O)=O)N)C=C1I)C2=CC(I)=C(O)C=C2

Synonyms:

• (2S)-2-Azaniumyl-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate
• (S)-2-Amino-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoicacid
• 3',5-Triiodo-L-Thyronin
• 3,3',5-Triiodothyronine
• 3,3′,5-Triiodo-<span class="text-smallcaps">L</span>-thyronine
• 3,3′,5-Triiodothyronine
• 3,5,3'-Triiodothyronine
• 4-(3-Iodo-4-Hydroxyphenoxy)-3,5-Diiodophenylalanine
• 4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenylalanine
• 5-Diiodophenyl)-3-(4-(4-Hydroxy-3-Iodophenoxy)-L-Alanin
• <span class="text-smallcaps">L</span>-3,3′,5-Triiodothyronine
• <span class="text-smallcaps">L</span>-Liothyronine
• <span class="text-smallcaps">L</span>-T₃
• <span class="text-smallcaps">L</span>-Triiodothyronine
• <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-
• Alanine, 3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-, <span class="text-smallcaps">L</span>-
• Alanine, 3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-, L-
• Cyronine
• Cytomel
• L-3,3',5-Triiodothyronine
• L-3,3,5-Triiodothyronine, Free Acid
• L-3-(4-(4-Hydroxy-3-Iodophenoxy)-3,5-Diiodophenyl)Alanine
• L-Liothyronine
• L-T3
• L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-
• L-triiodothyronine
• Liothyronin
• Liothyronine
• Liotironina
• Nsc 80203
• O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-<span class="text-smallcaps">L</span>-tyrosine
• O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine
• O-(4-hydroxyphenyl)-2,3,5-triiodotyrosine
• T3
• T3 (Hormone)
• T3 (amino acid)
• T₃
• T₃ (Hormone)
• T₃ (amino acid)
• Thyronine, 3,3',5-triiodo-, L-
• Thyronine, 3,3′,5-triiodo-, <span class="text-smallcaps">L</span>-
• Tresitope
• Triiodo-<span class="text-smallcaps">L</span>-thyronine
• Triiodo-L-thyronine
• Triiodothyronine

3,3',5-Triiodo-L-thyronine

CAS: 6893-02-3

Formula: C₁₅H₁₂I₃NO₄

Purity: >98.0%(HPLC)(T)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 650.98

Ref: 3B-T0453

3,3',5-Triiodo-L-thyronine, 95%

CAS: 6893-02-3

Using video intensification fluorescence microscopy and tetramethylrhodamine (Rho)-labeled 3, 3', 5-triiodo-L-thyronine (T3),the uptake of T3 by cultured mouse fibroblasts was studied. The binding of 3, 3', 5-triiodo-L-thyronine (T3) to GH3 rat pituitary tumor cells was studied at 15 degrees C and

Formula: C₁₅H₁₂I₃NO₄

Purity: 95%

Color and Shape: White to cream to yellow to pale brown, Powder or crystalline powder or solid

Molecular weight: 650.98

Ref: 02-H34068

Liothyronine

CAS: 6893-02-3

Amino-acid derivatives

Formula: C₁₅H₁₂I₃NO₄

Color and Shape: White Cream Powder

Molecular weight: 650.79005

Ref: 45-1368008

3,3',5-Triiodo-L-Thyronine

CAS: 6893-02-3

3,3',5-Triiodo-L-Thyronine

Formula: C₁₅H₁₂I₃NO₄

Purity: >97%

Molecular weight: 650.97

Ref: 54-OR1010733

Liothyronine (Levothyroxine EP Impurity A)

CAS: 6893-02-3

Formula: C₁₅H₁₂I₃NO₄

Molecular weight: 650.98

Ref: 4Z-L-242001

Liothyronine

CAS: 6893-02-3

Liothyronine

Formula: C₁₅H₁₂I₃NO₄

Purity: ≥98%

Molecular weight: 650.97

Ref: 54-BUP15946

3,3'',5-Triiodo-L-thyronine

CAS: 6893-02-3

Formula: C₁₅H₁₂I₃NO₄

Purity: ≥ 98.0%

Color and Shape: White to off-white or faint yellow powder

Molecular weight: 650.97

Ref: 7W-GE2741

3,3',5-Triiodo-L-thyronine

CAS: 6893-02-3

Formula: C₁₅H₁₂I₃NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 650.9735

Ref: IN-DA0032GT

Liothyronine (Standard)

CAS: 6893-02-3

Liothyronine (Standard) is a synthetic thyroid hormone regulating metabolism and used for hyperthyroidism model construction.

Formula: C₁₅H₁₂I₃NO₄

Molecular weight: 650.9735

Ref: TM-TMSM-3271

3,3’,5-Triiodo-L-thyronine

Controlled Product

CAS: 6893-02-3

Formula: C₁₅H₁₂I₃NO₄

Color and Shape: Neat

Molecular weight: 650.97

Ref: TR-T795380

Liothyronine

CAS: 6893-02-3

Liothyronine (Tresitope) is an active form of thyroid hormone, binding to β1 thyroid hormone receptor (TRβ1), and activates its activity.

Formula: C₁₅H₁₂I₃NO₄

Purity: 98.50% - 99.33%

Color and Shape: White Solid

Molecular weight: 650.9735

Ref: TM-T1653

Liothyronine

CAS: 6893-02-3

Formula: C₁₅H₁₂I₃NO₄

Molecular weight: 650.98

Ref: ST-EA-CP-L45000

3,3',5-Triiodo-L-thyronine

CAS: 6893-02-3

Triiodothyronine (T3) is a thyroid hormone that has a high affinity for the thyrotropin receptor. It regulates the metabolic rate, cell specific transcriptional regulation, and transcriptional regulation of genes involved in fatty acid synthesis. T3 is synthesized from the amino acid tyrosine through a series of reactions catalyzed by enzymes such as tyrosine hydroxylase, thyroperoxidase, and type 2 iodothyronine deiodinase. The enzyme thyroid peroxidase converts inactive T3 to the active form of T3 (triiodothyronine). In addition, triiodothyronine can be converted to reverse T3 (rT3), which is inactive. Triiodothyronine has an optimal ph of 7.4-8.0 and an optimum igf-i concentration of 100 ng/ml, where it can stimulate growth hormone release from the anterior pituitary gland.

Formula: C₁₅H₁₂I₃NO₄

Purity: Min. 95 Area-%

Color and Shape: Off-White Powder

Molecular weight: 650.97 g/mol

Ref: 3D-FT28506

3.3‘.5-Triiodo-L-thyronine in Methanol

CAS: 6893-02-3

Methanol

Formula: C₁₅H₁₂I₃NO₄

Color and Shape: Solid

Molecular weight: 650.97

Ref: BE-MU-2550XM-100

Liothyronine

CAS: 6893-02-3

Formula: C₁₅H₁₂I₃NO₄

Color and Shape: Solid

Molecular weight: 650.97

Ref: BE-RMCT176020

Triiodothyronine-[13C6] hydrochloride in Methanol

CAS: 6893-02-3

Methanol

Formula: C₁₅H₁₂I₃NO₄

Color and Shape: Solid

Molecular weight: 650.97

Ref: BE-MC-2550C6XM-100

Triiodothyronine-[13C6] hydrochloride (L-Liothyronine; T3)

CAS: 6893-02-3

Formula: C₁₅H₁₂I₃NO₄

Color and Shape: Solid

Molecular weight: 650.97

Ref: BE-MC-2550C6

3.3‘.5-Triiodo-L-thyronine

CAS: 6893-02-3

Formula: C₁₅H₁₂I₃NO₄

Color and Shape: Solid

Molecular weight: 650.97

Ref: BE-MU-2550

3,3,5-Triiodo-L-Thyronine extrapure, 95%

CAS: 6893-02-3

Formula: C₁₅H₁₂I₃NO₄

Purity: min. 95%

Color and Shape: White to off-white, Powder

Molecular weight: 650.98

Ref: SR-35241

Liothyronine

CAS: 6893-02-3

Purity: 98%

Molecular weight: 650.9769897

Ref: 10-F787598