CAS 69-65-8

Mannitol

Description:

Mannitol, with the CAS number 69-65-8, is a sugar alcohol that is classified as a polyol. It is a white, crystalline powder that is sweet-tasting and soluble in water. Mannitol is commonly used as a low-calorie sweetener and is often found in sugar-free products. Its chemical formula is C6H14O6, and it has a molecular weight of approximately 182.17 g/mol. Mannitol is known for its osmotic diuretic properties, making it useful in medical applications, particularly in the treatment of increased intracranial pressure and in renal protection during surgery. Additionally, it is utilized in the pharmaceutical industry as a bulking agent and stabilizer for proteins and vaccines. Mannitol is generally recognized as safe (GRAS) by regulatory agencies, but excessive consumption can lead to gastrointestinal discomfort. Its stability under various conditions and low glycemic index make it a valuable ingredient in both food and pharmaceutical formulations.

Formula: C₆H₁₄O₆

InChI: InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1

InChI key: InChIKey=FBPFZTCFMRRESA-KVTDHHQDSA-N

SMILES: [C@H]([C@@H]([C@@H](CO)O)O)([C@@H](CO)O)O

Synonyms:

• (2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexaol
• <span class="text-smallcaps">D</span>-(-)-Mannitol
• <span class="text-smallcaps">D</span>-Mannit
• Ai3-19511
• Brightmoon
• Bronchitol
• Cerestar 16700
• Cordycepic acid
• D-Mannit
• D-Mannitol
• D-manitol
• DL-Mannitol
• Diosmol
• E 421
• Granitol S
• Granutol F
• Granutol R
• Granutol S
• Hexahydroxyhexane
• Hexitol
• Isotol
• L-altritol
• M 100
• Manicol
• Maniton S
• Manna sugar
• Mannidex
• Mannidex 16700
• Mannigen
• Mannistol
• Mannit
• Mannit 60
• Mannit P
• Mannit Q
• Mannit S
• Mannite
• Mannitol 300DC
• Mannitol 35
• Mannitol 60
• Mannitol P 60
• Mannitol SD 200
• Mannitol, <span class="text-smallcaps">D</span>-
• Mannitol, D-
• Mannitol, Powder
• Mannitolum
• Mannogem 2080
• Mannogem EZ
• Marine Crystal
• Nonpareil 108
• Nonpareil 108(200)
• Nsc 9256
• Orocell 200
• Osmitrol
• Osmosal
• Parteck 300
• Parteck Delta M
• Parteck M 100
• Parteck M 200
• Parteck M 300
• Partek M
• Pearlitol
• Pearlitol 100
• Pearlitol 100SD
• Pearlitol 160C
• Pearlitol 2005D
• Pearlitol 200SD
• Pearlitol 25C
• Pearlitol 50C
• Pearlitol SD 100
• Perlitol SD 200
• Perteck M
• PharmMannidex
• PharmMannidex 16701

D(-)-Mannitol (USP, BP, Ph. Eur.) pure

CAS: 69-65-8

D(-)-Mannitol (USP, BP, Ph. Eur.) pure

Formula: C₆H₁₄O₆

Purity: Pharma Grade

Color and Shape: Solid

Molecular weight: 182.17g/mol

Ref: 54-BI142067

D-Mannitol RS

CAS: 69-65-8

Color and Shape: White Solid Crystals Or Powder

Ref: 2K-1156300021

Human Growth Hormone RS

CAS: 10028-24-7, 12629-01-5, 13472-35-0, 56-40-6, 69-65-8

Color and Shape: White Solid

Ref: 2K-3001000021

Mannitol

CAS: 69-65-8

Formula: C₆H₁₄O₆

Molecular weight: 182.17

Ref: ST-EA-CP-M41000

D-Mannitol-1,1'-d2

Controlled Product

CAS: 69-65-8

Applications Labeled D-Mannitol is widespread in plants and plant exudates; obtained from manna and seaweeds. D-Mannitol is used in the food industry as anticaking and free-flow agent, flavoring agent, lubricant and release agent, stabilizer and thickener and nutritive sweetener.
References Pigman, W., et al.: The Carbohydrates, 249 (1957), Makkee, M., et al.: Chem. Commun., 930 (1980),

Formula: C₆D₂H₁₂O₆

Color and Shape: Neat

Molecular weight: 184.184

Ref: TR-M165009

D-Mannitol

Controlled Product

CAS: 69-65-8

Applications D-Mannitol is widespread in plants and plant exudates; obtained from manna and seaweeds. D-Mannitol is used in the food industry as anticaking and free-flow agent, flavoring agent, lubricant and release agent, stabilizer and thickener and nutritive sweetener.
References Pigman, W., et al.: The Carbohydrates, 249 (1957), Makkee, M., et al.: Chem. Commun., 930 (1980),

Formula: C₆H₁₄O₆

Color and Shape: Neat

Molecular weight: 182.17

Ref: TR-M165000

D-Mannitol-1,2-13C2

Controlled Product

CAS: 69-65-8

Applications Labeled D-Mannitol is widespread in plants and plant exudates; obtained from manna and seaweeds. D-Mannitol is used in the food industry as anticaking and free-flow agent, flavoring agent, lubricant and release agent, stabilizer and thickener and nutritive sweetener.
References Pigman, W., et al.: The Carbohydrates, 249 (1957); Makkee, M., et al.: Chem. Commun., 930 (1980);

Formula: C₄₁₃C₂H₁₄O₆

Color and Shape: Neat

Molecular weight: 184.16

Ref: TR-M165006

D-Mannitol-d8

Controlled Product

CAS: 69-65-8

Applications Labelled D-Mannitol (M165000). D-Mannitol is widespread in plants and plant exudates; obtained from manna and seaweeds. D-Mannitol is used in the food industry as anticaking and free-flow agent, flavoring agent, lubricant and release agent, stabilizer and thickener and nutritive sweetener.
References Pigman, W., et al.: The Carbohydrates, 249 (1957), Makkee, M., et al.: Chem. Commun., 930 (1980),

Formula: C₆D₈H₆O₆

Color and Shape: Neat

Molecular weight: 190.22

Ref: TR-M165002

D-Mannitol-UL-13C6

CAS: 69-65-8

Applications Labeled D-Mannitol is widespread in plants and plant exudates; obtained from manna and seaweeds. D-Mannitol is used in the food industry as anticaking and free-flow agent, flavoring agent, lubricant and release agent, stabilizer and thickener and nutritive sweetener.
References Pigman, W., et al.: The Carbohydrates, 249 (1957), Makkee, M., et al.: Chem. Commun., 930 (1980),

Formula: C₆H₁₄O₆

Color and Shape: White Solid

Molecular weight: 188.13

Ref: TR-M165008

D-Mannitol-[1-13C;1,1'-d2]

Controlled Product

CAS: 69-65-8

Applications Labeled D-Mannitol is widespread in plants and plant exudates; obtained from manna and seaweeds. D-Mannitol is used in the food industry as anticaking and free-flow agent, flavoring agent, lubricant and release agent, stabilizer and thickener and nutritive sweetener.
References Pigman, W., et al.: The Carbohydrates, 249 (1957), Makkee, M., et al.: Chem. Commun., 930 (1980),

Formula: CC₅H₁₂D₂O₆

Color and Shape: Neat

Molecular weight: 185.18

Ref: TR-M165012

D-Mannitol

CAS: 69-65-8

Mannitol is a sugar alcohol occurring widely in plants and they are exudates, for example, in olive and plane trees (Collins, 2006). It is produced commercially by the catalytic hydrogenation of fructose (Zelin, 2019). Mannitol is used extensively in food and pharmaceutical industries because of its unique functional properties. It is about 50% as sweet as sucrose and has a desirable cooling effect often used to mask bitter tastes. Mannitol is non-cariogenic and has a low caloric content. Mannitol is an osmotic diuretic that is metabolically inert in humans and is used for: the promotion of diuresis before irreversible renal failure becomes established, the promotion of urinary excretion of toxic substances, as an Antiglaucoma agent, and as a renal function diagnostic aid (O’Neil, 2013). Additonally, in 2020, mannitol was approved by the FDA as add-on maintenance therapy for the control of pulmonary symptoms associated with cystic fibrosis in adult patients (McKenna, 2020).

Formula: C₆H₁₄O₆

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 182.17 g/mol

Ref: 3D-MM02190

D-Mannitol extrapure, 98.5%

CAS: 69-65-8

Formula: C₆H₁₄O₆

Purity: min.98.5%

Color and Shape: White, Crystalline Powder, Clear, Colourless

Molecular weight: 182.17

Ref: SR-24248

D-Mannitol Sterile (γ Irradiated)

CAS: 69-65-8

Purity: 98.5%

Color and Shape: White, Crystalline powder, Clear, colourless solution

Ref: SR-40828

D-Mannitol ACS, 99%

CAS: 69-65-8

Formula: C₆H₁₄O₆

Purity: min. 99%

Color and Shape: Crystalline powder, White, Clear, Colourless

Molecular weight: 182.17

Ref: SR-79887

D-Mannitol ACS, ExiPlus, Multi-Compendial, 99%

CAS: 69-65-8

Formula: C₆H₁₄O₆

Purity: min.99.0%

Color and Shape: White, Crystalline powder, Clear, Colourless

Molecular weight: 182.17

Ref: SR-21304

D-Mannitol-1,6-13C2

Controlled Product

CAS: 69-65-8

Applications Labeled D-Mannitol is widespread in plants and plant exudates; obtained from manna and seaweeds. D-Mannitol is used in the food industry as anticaking and free-flow agent, flavoring agent, lubricant and release agent, stabilizer and thickener and nutritive sweetener.
References Pigman, W., et al.: The Carbohydrates, 249 (1957), Makkee, M., et al.: Chem. Commun., 930 (1980),

Formula: C₄₁₃C₂H₁₅O₆

Color and Shape: Neat

Molecular weight: 184.16

Ref: TR-M165007

D-Mannitol - EP

CAS: 69-65-8

Mannitol is a sugar alcohol occurring widely in plants and they are exudates, for example, in olive and plane trees (Collins, 2006). It is produced commercially by the catalytic hydrogenation of fructose (Zelin, 2019). Mannitol is used extensively in food and pharmaceutical industries because of its unique functional properties. It is about 50% as sweet as sucrose and has a desirable cooling effect often used to mask bitter tastes. Mannitol is non-cariogenic and has a low caloric content. Mannitol is an osmotic diuretic that is metabolically inert in humans and is used for: the promotion of diuresis before irreversible renal failure becomes established, the promotion of urinary excretion of toxic substances, as an Antiglaucoma agent, and as a renal function diagnostic aid (O’Neil, 2013). Additonally, in 2020, mannitol was approved by the FDA as add-on maintenance therapy for the control of pulmonary symptoms associated with cystic fibrosis in adult patients (McKenna, 2020).

Formula: C₆H₁₄O₆

Purity: Min. 97 Area-%

Color and Shape: White Powder

Molecular weight: 182.17 g/mol

Ref: 3D-MM63310

D-Mannit 1000 µg/mL in Methanol

Controlled Product

CAS: 69-65-8

Formula: C₆H₁₄O₆

Color and Shape: Single Solution

Molecular weight: 182.17

Ref: 04-A14752000ME-1000