CAS 69002-84-2
:5-Hydroxydiclofenac
Description:
5-Hydroxydiclofenac is a derivative of diclofenac, a non-steroidal anti-inflammatory drug (NSAID) commonly used for its analgesic and anti-inflammatory properties. This compound is characterized by the presence of a hydroxyl group at the 5-position of the phenyl ring, which alters its pharmacological profile compared to its parent compound. It is typically a white to off-white solid and is soluble in organic solvents but has limited solubility in water. The molecular structure of 5-hydroxydiclofenac contributes to its potential therapeutic effects, including anti-inflammatory and analgesic activities, while also influencing its metabolic pathways and bioavailability. The compound is of interest in pharmacological research, particularly in understanding the metabolism of diclofenac and its metabolites, as well as their respective biological activities. Safety and efficacy profiles are essential considerations in its application, as with all pharmaceutical agents.
Formula:C14H11Cl2NO3
InChI:InChI=1S/C14H11Cl2NO3/c15-10-2-1-3-11(16)14(10)17-12-5-4-9(18)6-8(12)7-13(19)20/h1-6,17-18H,7H2,(H,19,20)
InChI key:InChIKey=VNQURRWYKFZKJZ-UHFFFAOYSA-N
SMILES:N(C1=C(CC(O)=O)C=C(O)C=C1)C2=C(Cl)C=CC=C2Cl
Synonyms:- 2-(2-((2,6-Dichlorophenyl)Amino)-5-Hydroxyphenyl)Acetic Acid
- 2-[(2,6-Dichlorophenyl)amino]-5-hydroxybenzeneacetic acid
- 2-[2-(2,6-Dichloroanilino)-5-hydroxyphenyl]acetic acid
- 5-Hydroxydiclofenac
- Benzeneacetic Acid, 2-[(2,6-Dichlorophenyl)Amino]-5-Hydroxy-
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Found 8 products.
5-hydroxy Diclofenac
CAS:Formula:C14H11Cl2NO3Purity:95%Color and Shape:SolidMolecular weight:312.14802-(2-((2,6-Dichlorophenyl)amino)-5-hydroxyphenyl)acetic acid
CAS:2-(2-((2,6-Dichlorophenyl)amino)-5-hydroxyphenyl)acetic acidPurity:98%Molecular weight:312.15g/mol5-hydroxy Diclofenac
CAS:5-hydroxy Diclofenac, a CYP3A4-formed NSAID diclofenac metabolite, inhibits COX-1/2 with varying IC50 values.Formula:C14H11Cl2NO3Color and Shape:SolidMolecular weight:312.155-Hydroxy Diclofenac
CAS:<p>Applications A metabolite of Diclofenac, a nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kretz-Rommel, A., et al.: Toxicol. Appl. Pharmacol., 120, 155 (1993), Petronilli, V., et al.: J. Biol. Chem., 269, 16638 (1994), Bort, R., et al.: J. Pharmacol. Exp. Ther., 288, 65 (1998), Poon, G., et al.: Drug Metab. Dispos., 29, 1608 (2001),<br></p>Formula:C14H11Cl2NO3Color and Shape:Purple To Light RedMolecular weight:312.152-(2-((2,6-Dichlorophenyl)amino)-5-hydroxyphenyl)acetic acid
CAS:Purity:98.00%Molecular weight:312.1499939
