CAS 69004-04-2

Ponazuril

Description:

Ponazuril is a chemical compound primarily recognized for its use as an antiparasitic agent, particularly in veterinary medicine. It is a member of the triazine class of compounds and is known for its efficacy against various protozoan parasites, including those responsible for coccidiosis in animals. The substance exhibits a broad spectrum of activity and is often utilized in the treatment of infections caused by Eimeria species in livestock and pets. Ponazuril functions by inhibiting the synthesis of nucleic acids in the parasites, ultimately leading to their death. In terms of physical properties, Ponazuril is typically presented as a white to off-white powder, which is soluble in organic solvents but has limited solubility in water. Its safety profile indicates that it has a low toxicity in the recommended dosages for animals, making it a preferred choice in veterinary therapeutics. As with any pharmaceutical agent, proper dosing and adherence to veterinary guidelines are essential to ensure efficacy and minimize potential side effects.

Formula: C₁₈H₁₄F₃N₃O₆S

InChI: InChI=1/C18H14F3N3O6S/c1-10-9-11(24-16(26)22-15(25)23(2)17(24)27)3-8-14(10)30-12-4-6-13(7-5-12)31(28,29)18(19,20)21/h3-9H,1-2H3,(H,22,25,26)

InChI key: InChIKey=VBUNOIXRZNJNAD-UHFFFAOYSA-N

SMILES: O=C1N(C(=O)NC(=O)N1C)C2=CC(C)=C(OC3=CC=C(S(C(F)(F)F)(=O)=O)C=C3)C=C2

Synonyms:

• 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1-methyl-3-[3-methyl-4-[4-[(trifluoromethyl)sulfonyl]phenoxy]phenyl]-
• 1-Methyl-3-(3-Methyl-4-{4-[(Trifluoromethyl)Sulfonyl]Phenoxy}Phenyl)-1,3,5-Triazinane-2,4,6-Trione
• 1-Methyl-3-(4-(p-((trifluoromethyl)sulfonyl)phenoxy)-m-tolyl)-s-triazine-2,4,6(1H,3H,5H)-trione
• 1-Methyl-3-[3-methyl-4-[4-(trifluoromethylsulfonyl)phenoxy]phenyl]-1,3,5-triazinane-2,4,6-trione
• 1-Methyl-3-[3-methyl-4-[4-[(trifluoromethyl)sulfonyl]phenoxy]phenyl]-1,3,5-triazine-2,4,6(1H,3H,5H)-trione
• BAY-Vi 9143
• Marquis
• Toltrazuril sulfone
• Ponazuril
• Ponazuril ，Toltrazuril sulfone
• 1-Methyl-3-{3-methyl-4-[4-(trifluoromethylsulfonyl)phenoxy]phenyl}-1,3,5-triazine-2,4,6(1H,3H,5H)-trione
• ToltrazurilSulfone
• Unii-jpw84as66u
• Veterinary Ponazuril
• Ponazurilr
• Toltrazuril Sulfone Standard
• Ponazuril [inn]

1-methyl-3-{3-methyl-4-[4-(trifluoromethylsulfonyl)phenoxy]phenyl}-1,3,5-triazine-2,4,6(1h,3h,5h)-trione

CAS: 69004-04-2

Formula: C₁₈H₁₄F₃N₃O₆S

Purity: 99%

Color and Shape: Solid

Molecular weight: 457.3805

Ref: IN-DA005M6C

Toltrazuril (sulfone)

CAS: 69004-04-2

Toltrazuril (sulfone)

Purity: ≥98%

Molecular weight: 457.38g/mol

Ref: 54-BUP11285

Toltrazuril Sulfone (Ponazuril)

CAS: 69004-04-2

Formula: C₁₈H₁₄F₃N₃O₆S

Color and Shape: White To Off-White Solid

Molecular weight: 457.38

Ref: 4Z-T-451

Ponazuril

CAS: 69004-04-2

Formula: C₁₈H₁₄F₃N₃O₆S

Color and Shape: Neat

Molecular weight: 457.38

Ref: 04-C16283700

Toltrazuril (sulfone)

CAS: 69004-04-2

Toltrazuril sulfone (Ponazuril) is an antiprotozoal agent that acts upon Coccidia parasites.

Formula: C₁₈H₁₄F₃N₃O₆S

Purity: 98.75% - 98.84%

Color and Shape: Solid

Molecular weight: 457.38

Ref: TM-T5052

Ponazuril

Controlled Product

CAS: 69004-04-2

Applications Antiprotazoal, used to treat Equine Protozoal Myeloencephalitis (EPM).
References Mitchell, S., et al.: J. Parasitol., 90, 639 (2004), Didikolu, L., et al.: J. Vet. Pharmacol. Ther., 32, 368 (2009), Martinez-Villalba, A., et al.: Anal. Bioanal. Chem., 397, 2893 (2010),

Formula: C₁₈H₁₄F₃N₃O₆S

Color and Shape: Off White

Molecular weight: 457.38

Ref: TR-P689425

1-Methyl-3-[3-methyl-4-[4-[(trifluoromethyl)sulfonyl]phenoxy]phenyl]-1,3,5-triazine-2,4,6(1H,3H,5H)-trione

CAS: 69004-04-2

Ponazuril is a veterinary drug that belongs to the group of chemotherapeutics. It is used in the treatment of endoparasites, such as nematodes and cestodes, which are parasites that live inside the human body. Ponazuril is administered orally or by injection and has been shown to have minimal toxicity in CD-1 mice. Ponazuril binds to DNA polymerase, inhibiting RNA synthesis and protein synthesis. This leads to cell death by apoptosis and necrosis. The drug also inhibits DNA replication in the parasite and blocks parasite growth.

Formula: C₁₈H₁₄F₃N₃O₆S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 457.38 g/mol

Ref: 3D-FM27105

1-methyl-3-{3-methyl-4-[4-(trifluoromethylsulfonyl)phenoxy]phenyl}-1,3,5-triazine-2,4,6(1h,3h,5h)-trione

CAS: 69004-04-2

Purity: 99%

Molecular weight: 457.3800049

Ref: 10-F866283

Toltrazuril Sulfone

CAS: 69004-04-2

Formula: C₁₈H₁₄F₃N₃O₆S

Molecular weight: 457.38

Ref: ST-EA-CP-T168004