CAS 69045-79-0

2-Chloro-5-iodopyridine

Description:

2-Chloro-5-iodopyridine is a heterocyclic organic compound characterized by a pyridine ring substituted with chlorine and iodine atoms. It features a chlorine atom at the 2-position and an iodine atom at the 5-position of the pyridine ring, which contributes to its reactivity and potential applications in organic synthesis. This compound is typically a colorless to pale yellow liquid or solid, depending on its form and purity. It is soluble in organic solvents such as ethanol and dichloromethane but has limited solubility in water. The presence of halogen substituents enhances its electrophilic properties, making it useful in various chemical reactions, including nucleophilic substitutions and coupling reactions. 2-Chloro-5-iodopyridine is often employed in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. As with many halogenated compounds, it should be handled with care due to potential toxicity and environmental concerns. Proper safety measures, including the use of personal protective equipment, are recommended when working with this substance.

Formula: C₅H₃ClIN

InChI: InChI=1S/C5H3ClIN/c6-5-2-1-4(7)3-8-5/h1-3H

InChI key: InChIKey=QWLGCWXSNYKKDO-UHFFFAOYSA-N

SMILES: IC=1C=CC(Cl)=NC1

Synonyms:

• 2-Chloro-5-Indopyridine
• 2-Chloro-5-Iodopyridine 98% 2G
• 2-Chloro-5-iodopyridine,98%
• 2-Choro-5-Iodopyridine
• 5-Iodo-2-chloropyridine
• Pyridine, 2-chloro-5-iodo-
• 2-Chloro-5-iodopyridine

2-Chloro-5-iodopyridine

CAS: 69045-79-0

Formula: C₅H₃ClIN

Purity: >98.0%(GC)

Color and Shape: White to Amber powder to crystal

Molecular weight: 239.44

Ref: 3B-C2341

2-Chloro-5-iodopyridine, 98%

CAS: 69045-79-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₅H₃ClIN

Purity: 98%

Color and Shape: Yellow to orange to pale brown, Crystals or powder or crystalline powder

Molecular weight: 239.44

Ref: 02-B25271

2-Chloro-5-iodopyridine

CAS: 69045-79-0

Formula: C₅H₃ClIN

Purity: 98%

Color and Shape: Solid

Molecular weight: 239.4415

Ref: IN-DA003GZ2

2-Chloro-5-iodopyridine

CAS: 69045-79-0

2-Chloro-5-iodopyridine

Formula: C₅H₃ClIN

Purity: 98%

Color and Shape: faint brown crystalline solid

Molecular weight: 239.44g/mol

Ref: 54-OR15739

2-Chloro-5-iodopyridine

CAS: 69045-79-0

Formula: C₅H₃ClIN

Purity: ≥ 98.0%

Color and Shape: White to light yellow solid

Molecular weight: 239.44

Ref: 7W-GK8041

2-Chloro-5-iodopyridine

CAS: 69045-79-0

Formula: C₅H₃ClIN

Purity: 98%

Color and Shape: Solid

Molecular weight: 239.44

Ref: 10-F046448

2-Chloro-5-iodopyridine

CAS: 69045-79-0

2-Chloro-5-iodopyridine is a synthetic compound that binds to nicotinic acetylcholine receptors, and is an agonist of these receptors. It has been shown to bind selectively to the alpha4beta2 subtype of these receptors. 2-Chloro-5-iodopyridine binds to the receptor by means of hydrogen bonding and chelation, which results in the activation of the receptor. This process leads to increased levels of catecholamines and other neurotransmitters, which causes changes in the heart rate and blood pressure. 2-Chloro-5-iodopyridine is a halogenated organic molecule that can be synthesized from sodium trifluoroacetate in two steps: first with chlorination followed by iodination. The synthesis can be carried out using copper (II) chloride as a catalyst or copper (I) iodide as an oxidant, followed by reduction with sodium borohydride.

Formula: C₅H₃ClIN

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 239.44 g/mol

Ref: 3D-FC16330