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CAS 69049-74-7

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Nedocromil sodium

Description:
Nedocromil sodium is a medication primarily used as an anti-inflammatory agent in the treatment of asthma and allergic conditions. It belongs to the class of compounds known as mast cell stabilizers, which work by inhibiting the release of inflammatory mediators from mast cells, thereby reducing bronchoconstriction and inflammation in the airways. The substance is typically administered via inhalation, allowing for localized effects in the respiratory system. Nedocromil sodium is characterized by its relatively low solubility in water, which influences its formulation and delivery methods. It is often presented as a sodium salt, enhancing its stability and bioavailability. The compound is generally well-tolerated, with a favorable safety profile, though it may cause mild side effects in some individuals. Its mechanism of action is distinct from that of corticosteroids and bronchodilators, making it a valuable option in asthma management, particularly for patients who experience exercise-induced bronchoconstriction or have a history of allergic reactions.
Formula:C19H15NNa2O7
InChI:InChI=1/C19H17NO7.2Na/c1-3-5-9-16-10(13(21)7-12(18(23)24)20(16)4-2)6-11-14(22)8-15(19(25)26)27-17(9)11;;/h6-8H,3-5H2,1-2H3,(H,23,24)(H,25,26);;/q;2*+1/p-2
InChI key:InChIKey=VFSSLTJVAPVYCU-UHFFFAOYSA-N
SMILES:C(CC)C1=C2C(=CC3=C1OC(C(O)=O)=CC3=O)C(=O)C=C(C(O)=O)N2CC.[Na]
Synonyms:
  • 4H-Pyrano(3,2-g)quinoline-2,8-dicarboxylic acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-, disodium salt
  • 4H-Pyrano[3,2-g]quinoline-2,8-dicarboxylic acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-, sodium salt (1:2)
  • Alocril
  • Disodium-9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano(3,2-g)quinoline-2,8-dicarboxylate
  • Fpl 59002Kp
  • Nedocromil disodium salt
  • Nedocromil sodium [USAN]
  • Rapitil
  • Tayled
  • Tilade
  • See more synonyms
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