CAS 69181-26-6

5-Carboxymethylaminomethyluridine

Description:

5-Carboxymethylaminomethyluridine is a modified nucleoside that features a uridine base with a carboxymethylaminomethyl substituent at the 5-position. This compound is notable for its role in various biochemical processes, particularly in the context of RNA biology and potential therapeutic applications. The presence of the carboxymethyl group enhances its solubility and may influence its interaction with other biomolecules. As a nucleoside derivative, it retains the characteristic ribose sugar and uracil base, which are essential for its function in nucleic acid structures. The compound is of interest in research related to nucleic acid modifications, and its unique structure may provide insights into the regulation of gene expression and the development of novel RNA-based therapeutics. Additionally, its CAS number, 69181-26-6, allows for precise identification in chemical databases, facilitating further studies and applications in medicinal chemistry and molecular biology.

Formula: C₁₂H₁₇N₃O₈

InChI: InChI=1/C12H17N3O8/c16-4-6-8(19)9(20)11(23-6)15-3-5(1-13-2-7(17)18)10(21)14-12(15)22/h3,6,8-9,11,13,16,19-20H,1-2,4H2,(H,17,18)(H,14,21,22)/t6-,8-,9-,11-/m1/s1

InChI key: InChIKey=VSCNRXVDHRNJOA-PNHWDRBUSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C=C(CNCC(O)=O)C(=O)NC2=O

Synonyms:

• 5-Carboxymethylaminomethyluridine
• Glycine, N-[(1,2,3,4-tetrahydro-2,4-dioxo-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-5-pyrimidinyl)methyl]-
• N-[(1,2,3,4-Tetrahydro-2,4-dioxo-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-5-pyrimidinyl)methyl]glycine
• Uridine, 5-[[(Carboxymethyl)Amino]Methyl]-
• [({1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl}methyl)amino]acetic acid (non-preferred name)
• Glycine, N-[(1,2,3,4-tetrahydro-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidinyl)methyl]-
• N-[(1,2,3,4-Tetrahydro-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidinyl)methyl]glycine
• Uridine-5-methylamino acetic acid
• 5-(((carboxymethyl)amino)methyl)uridine
• Uridine-5-methylamino acetic acid RNA-modified nucleoside cmnm5U

Uridine-5-methylamino   acetic acid

CAS: 69181-26-6

Formula: C₁₂H₁₇N₃O₈

Purity: 95%

Molecular weight: 331.2787

Ref: IN-DA006BVW

Uridine-5-methylamino acetic acid

CAS: 69181-26-6

Uridine-5-methylamino acetic acid

Purity: ≥95%

Molecular weight: 331.28g/mol

Ref: 54-BUP21691

Uridine-5-methylamino acetic acid

CAS: 69181-26-6

Uridine-5-methylamino acetic acid(CMAMU) is a derivative of glycine and uracil, commonly used to study the synthesis and translation processes of nucleic acids.

Formula: C₁₂H₁₇N₃O₈

Color and Shape: Solid

Molecular weight: 331.28

Ref: TM-TNU0166

5-Carboxymethylaminomethyluridine

CAS: 69181-26-6

5-Carboxymethylaminomethyluridine is a nucleoside analogue that is used in molecular modeling studies to investigate the role and interactions of uridine in the mitochondrial ribosome. It has been shown to bind to the mitochondrial ribosome, which may be due to hydrogen bonding interactions with adenine. 5-Carboxymethylaminomethyluridine also inhibits protein synthesis at the level of translation by inhibiting group P2 of eukaryotic cytosolic ribosomes. This inhibition results in decreased production of proteins necessary for mitochondrial biogenesis.

Formula: C₁₂H₁₇N₃O₈

Purity: Min. 95 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 331.28 g/mol

Ref: 3D-NC159491

5-Carboxymethylaminomethyluridine

Controlled Product

CAS: 69181-26-6

Formula: C₁₂H₁₇N₃O₈

Color and Shape: Neat

Molecular weight: 331.279

Ref: TR-C175983