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CAS 69224-79-9

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Beclomethasone 21-propionate

Description:
Beclomethasone 21-propionate is a synthetic corticosteroid primarily used for its anti-inflammatory and immunosuppressive properties. It is commonly employed in the treatment of various allergic and inflammatory conditions, particularly in respiratory diseases such as asthma and allergic rhinitis. The substance is characterized by its ability to reduce inflammation and suppress the immune response, making it effective in managing symptoms associated with these conditions. Beclomethasone 21-propionate is typically administered via inhalation or topical formulations, allowing for localized effects with minimal systemic absorption. Its chemical structure features a steroid backbone, which is essential for its biological activity, and it is known for its relatively high potency and low systemic side effects compared to other corticosteroids. The compound is generally well-tolerated, although potential side effects may include local irritation or, in rare cases, systemic effects with prolonged use. Overall, Beclomethasone 21-propionate is a valuable therapeutic agent in the management of inflammatory disorders.
Formula:C25H33ClO6
InChI:InChI=1S/C25H33ClO6/c1-5-21(30)32-13-20(29)25(31)14(2)10-18-17-7-6-15-11-16(27)8-9-22(15,3)24(17,26)19(28)12-23(18,25)4/h8-9,11,14,17-19,28,31H,5-7,10,12-13H2,1-4H3/t14-,17-,18-,19-,22-,23-,24-,25-/m0/s1
InChI key:InChIKey=OPNPEZLXXKGRTA-XGQKBEPLSA-N
SMILES:C[C@@]12[C@]([C@]3([C@](Cl)([C@@H](O)C1)[C@]4(C)C(CC3)=CC(=O)C=C4)[H])(C[C@H](C)[C@@]2(C(COC(CC)=O)=O)O)[H]
Synonyms:
  • (11Beta,16Beta)-9-Chloro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Propanoate
  • (11β,16β)-9-Chloro-11,17-dihydroxy-16-methyl-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
  • (9Xi,11Beta,16Beta)-9-Chloro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Propanoate
  • 9-Chloro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 21-propionate
  • Beclomethasone 21-monopropionate
  • Beclomethasone 21-propionate
  • Pregna-1,4-diene-3,20-dione, 9-chloro-11,17-dihydroxy-16-methyl-21-(1-oxopropoxy)-, (11β,16β)-
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