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CAS 69304-38-7

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3′,5′-O-[1,1,3,3-Tetrakis(1-methylethyl)-1,3-disiloxanediyl]uridine

Description:
3′,5′-O-[1,1,3,3-Tetrakis(1-methylethyl)-1,3-disiloxanediyl]uridine is a modified nucleoside that features a uridine base linked to a siloxane moiety. This compound is characterized by its unique siloxane structure, which incorporates multiple isopropyl groups, enhancing its hydrophobic properties and potentially influencing its solubility and stability in biological systems. The presence of the siloxane linkage may also impart unique mechanical properties, making it of interest in various applications, including drug delivery and materials science. The modification at the 3′ and 5′ positions of the uridine enhances its resistance to enzymatic degradation, which is beneficial for therapeutic applications. Additionally, the compound's structure suggests potential interactions with biological macromolecules, which could be explored for its utility in biochemistry and molecular biology. Overall, this compound exemplifies the intersection of organic chemistry and biochemistry, showcasing how structural modifications can lead to novel functionalities.
Formula:C21H38N2O7Si2
InChI:InChI=1S/C21H38N2O7Si2/c1-12(2)31(13(3)4)27-11-16-19(29-32(30-31,14(5)6)15(7)8)18(25)20(28-16)23-10-9-17(24)22-21(23)26/h9-10,12-16,18-20,25H,11H2,1-8H3,(H,22,24,26)/t16-,18-,19-,20-/m1/s1
InChI key:InChIKey=KKLQDUCRZCCKHG-VBSBHUPXSA-N
SMILES:C(C)(C)[Si]1(C(C)C)O[Si](C(C)C)(C(C)C)OC[C@@]2([C@@](O1)([C@@H](O)[C@@H](O2)N3C(=O)NC(=O)C=C3)[H])[H]
Synonyms:
  • 3',5'-TIPS-Uridine
  • 3′,5′-O-(1,1,3,3-Tetraisopropyldisiloxan-1,3-diyl)uridine
  • 3′,5′-O-(Tetraisopropyldisiloxanediyl)uridine
  • 3′,5′-O-[1,1,3,3-Tetrakis(1-methylethyl)-1,3-disiloxanediyl]uridine
  • 6H-Furo[3,2-f]-1,3,5,2,4-trioxadisilocin, uridine deriv.
  • Uridine, 3′,5′-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-
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