9,11-Dioxo-15S-hydroxy-prost-13E-en-1-oic acid, commonly referred to as a prostaglandin derivative, is a complex organic compound characterized by its unique structure that includes multiple functional groups such as hydroxyl and carbonyl groups. This compound is part of the prostaglandin family, which are lipid compounds derived from fatty acids and play crucial roles in various physiological processes, including inflammation, blood flow regulation, and the modulation of immune responses. The presence of dioxo and hydroxy groups contributes to its reactivity and biological activity. Typically, prostaglandins exhibit a range of effects on smooth muscle contraction, platelet aggregation, and the modulation of gastric acid secretion. The specific stereochemistry, indicated by the "15S" designation, is essential for its biological activity, influencing how it interacts with receptors in the body. As with many prostaglandin derivatives, this compound may have potential therapeutic applications, although its stability and bioavailability can vary, impacting its efficacy in clinical settings.

Prostaglandin K
1
(PGK
1
) is a 9,11-diketo analog of PGE
1
or PGD
1
. It is a PGE
2
receptor subtype EP
1
agonist that has 387-fold reduced potency compared to PGE
2
.
1

9,11-DIOXO-15S-HYDROXY-PROST-13E-EN-1-OIC ACID

69413-73-6: 9,11-Dioxo-15S-hydroxy-prost-13E-en-1-oic acid, commonly referred to as a prostaglandin derivative, is a complex organic compound characterized by its unique structure that includes multiple functional groups such as hydroxyl and carbonyl groups. This compound is part of the prostaglandin family, which are lipid compounds derived from fatty acids and play crucial roles in various physiological processes, including inflammation, blood flow regulation, and the modulation of immune responses. The presence of dioxo and hydroxy groups contributes to its reactivity and biological activity. Typically, prostaglandins exhibit a range of effects on smooth muscle contraction, platelet aggregation, and the modulation of gastric acid secretion. The specific stereochemistry, indicated by the "15S" designation, is essential for its biological activity, influencing how it interacts with receptors in the body. As with many prostaglandin derivatives, this compound may have potential therapeutic applications, although its stability and bioavailability can vary, impacting its efficacy in clinical settings.

<p>Prostaglandin K1 (compound 46) is a structurally modified prostanoid analog with an EC50 and Ki of 2800 nM for the EP1 receptor.</p>

CAS 69413-73-6

9,11-DIOXO-15S-HYDROXY-PROST-13E-EN-1-OIC ACID

Prostaglandin K1

Ref: TM-T203123