CymitQuimica logo

CAS 69427-46-9

:

13-cis-Acitretin

Description:
13-cis-Acitretin, also known as 13-cis-retinoic acid, is a synthetic derivative of retinoic acid, primarily used in dermatology for the treatment of severe psoriasis and other skin disorders. It belongs to the class of retinoids, which are compounds related to vitamin A. The substance exhibits characteristics such as being a pale yellow to orange crystalline solid, with a relatively low solubility in water but good solubility in organic solvents like ethanol and dimethyl sulfoxide. Its mechanism of action involves modulating gene expression by activating nuclear retinoic acid receptors, which leads to effects on cell proliferation and differentiation. 13-cis-Acitretin is known for its potential side effects, including teratogenicity, which necessitates careful monitoring during use, especially in women of childbearing age. Additionally, it may cause mucocutaneous side effects, such as dryness and irritation. Due to its pharmacological properties, it is classified as a prescription medication and is subject to regulations regarding its use and distribution.
Formula:C21H26O3
InChI:InChI=1S/C21H26O3/c1-14(8-7-9-15(2)12-21(22)23)10-11-19-16(3)13-20(24-6)18(5)17(19)4/h7-13H,1-6H3,(H,22,23)/b9-7+,11-10+,14-8+,15-12-
InChI key:InChIKey=IHUNBGSDBOWDMA-UGOGCBOOSA-N
SMILES:C(=C/C(=C/C=C/C(=C\C(O)=O)/C)/C)\C1=C(C)C(C)=C(OC)C=C1C
Synonyms:
  • (2Z,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid
  • 13-cis-Acitretin
  • 13-cis-Etretin
  • 2,4,6,8-Nonatetraenoic acid, 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-, (2Z,4E,6E,8E)-
  • 2,4,6,8-Nonatetraenoic acid, 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-, (Z,E,E,E)-
  • 2,4,6,8-Nonatetraenoicacid,9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-,(Z,E,E,E)-
  • A.(2Z,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid
  • Isoacitretin
  • Isoetretin
  • Ro 13-7652
  • See more synonyms
Sort by
The purity filter is not visible because current products do not have associated purity data for filtering.
Found 6 products.