CAS 6943-17-5

6-nitroquinazolin-4(1H)-one

Description:

6-Nitroquinazolin-4(1H)-one is a heterocyclic organic compound characterized by its quinazoline structure, which consists of a fused benzene and pyrimidine ring. The presence of a nitro group at the 6-position and a carbonyl group at the 4-position contributes to its unique chemical properties. This compound typically appears as a yellow crystalline solid and is known for its potential biological activities, including antimicrobial and anticancer properties. It is soluble in organic solvents but may have limited solubility in water. The compound's reactivity can be attributed to the electron-withdrawing nature of the nitro group, which can influence its interactions with other molecules. Additionally, 6-nitroquinazolin-4(1H)-one can serve as a valuable intermediate in the synthesis of various pharmaceuticals and agrochemicals. Safety data should be consulted for handling, as with many nitro compounds, it may pose health risks if not managed properly. Overall, its structural features and biological relevance make it a compound of interest in medicinal chemistry and drug development.

Formula: C₈H₅N₃O₃

InChI: InChI=1/C8H5N3O3/c12-8-6-3-5(11(13)14)1-2-7(6)9-4-10-8/h1-4H,(H,9,10,12)

SMILES: c1cc2c(cc1N(=O)=O)c(ncn2)O

Synonyms:

• 4(1H)-quinazolinone, 6-nitro-
• 4(3H)-Quinazolinone, 6-nitro-
• 6-Nitrochinazolin-4(1H)-on
• 6-Nitroquinazolin-4(3H)-one

4(3H)​-​Quinazolinone, 6-​nitro-

CAS: 6943-17-5

Formula: C₈H₅N₃O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 191.1436

Ref: IN-DA006DYZ

6-Nitroquinazolin-4(3H)-one

CAS: 6943-17-5

6-Nitroquinazolin-4(3H)-one

Purity: 98%

Molecular weight: 191.14g/mol

Ref: 54-OR89960

6-Nitro-4-quinazolone

Controlled Product

CAS: 6943-17-5

Applications Intermediate in the preparation of anticancer agents and enzyme inhibitors.
References Alfaro, J., et al.: Drug Metab. Disposition, 37, 2393 (2009), Cha, M., et al.: J. Med. Chem., 52, 6880 (2009),

Formula: C₈H₅N₃O₃

Color and Shape: Neat

Molecular weight: 191.14

Ref: TR-N596450

6-Nitroquinazolin-4(3H)-one

CAS: 6943-17-5

Formula: C₈H₅N₃O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 191.146

Ref: 10-F210121