CAS 6946-29-8

p-Aminosalicylic acid hydrazide

Description:

p-Aminosalicylic acid hydrazide, also known as PAS or PASH, is a chemical compound that serves as an important agent in the treatment of tuberculosis. It is a derivative of salicylic acid, characterized by the presence of both an amino group and a hydrazide functional group. This compound typically appears as a white to off-white crystalline powder and is soluble in water and alcohol, which facilitates its use in pharmaceutical formulations. p-Aminosalicylic acid hydrazide exhibits antibacterial properties, particularly against Mycobacterium tuberculosis, making it effective in combination therapies for tuberculosis management. Its mechanism of action involves inhibiting the synthesis of folic acid in bacteria, thereby disrupting their growth and replication. Additionally, it is important to monitor for potential side effects, which may include gastrointestinal disturbances and hypersensitivity reactions. Overall, p-Aminosalicylic acid hydrazide is a valuable therapeutic agent in the fight against tuberculosis, particularly in cases resistant to first-line treatments.

Formula: C₇H₉N₃O₂

InChI: InChI=1S/C7H9N3O2/c8-4-1-2-5(6(11)3-4)7(12)10-9/h1-3,11H,8-9H2,(H,10,12)

InChI key: InChIKey=FYZGXAKJVDHGDR-UHFFFAOYSA-N

SMILES: C(NN)(=O)C1=C(O)C=C(N)C=C1

Synonyms:

• 230-108-5
• 4-Amino-2-Hydroxybenzohydrazide
• 4-Aminosalicylic acid hydrazide
• 6946-29-8
• Apacizin
• Apacizina
• Benzoic acid, 4-amino-2-hydroxy-, hydrazide
• NSC 57125
• PAS-Hydrazid
• Pasdrazide
• Salicylic acid, 4-amino-, hydrazide

4-Amino-2-hydroxybenzenecarbohydrazide

CAS: 6946-29-8

Formula: C₇H₉N₃O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 167.1653

Ref: IN-DA006D9T

4-Amino-2-Hydroxybenzohydrazide

CAS: 6946-29-8

4-Amino-2-Hydroxybenzohydrazide

Purity: 98%

Molecular weight: 167.17g/mol

Ref: 54-OR1011411

4-Aminosalicylic acid hydrazide

CAS: 6946-29-8

4-Aminosalicylic acid hydrazide is a reactive functional group that is used as an intermediate in organic synthesis. It has a structural formula of C6H7N3O2 and is a white solid. 4-Aminosalicylic acid hydrazide has been shown to be highly resistant to mycobacterium avium, and can be used for the treatment of tuberculosis. The reactivity of this compound was studied by gravimetric analysis. This reaction is also degradable due to the presence of chloride ions and amido groups.

Formula: C₇H₉N₃O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 167.17 g/mol

Ref: 3D-FA71315

4-Amino-2-hydroxybenzohydrazide

CAS: 6946-29-8

Purity: 97%

Color and Shape: Solid

Molecular weight: 167.1679993

Ref: 10-F691083

4-Amino-2-hydroxybenzohydrazide

CAS: 6946-29-8

4-Amino-2-hydroxybenzohydrazide is a useful organic compound for research related to life sciences. The catalog number is T67638 and the CAS number is 6946-29-8.

Formula: C₇H₉N₃O₂

Color and Shape: Solid

Molecular weight: 167.168

Ref: TM-T67638