CAS 69483-37-0

1,2-Di-O-hexadecyl-rac-glycero-3-phosphocholine

Description:

1,2-Di-O-hexadecyl-rac-glycero-3-phosphocholine, commonly referred to as DHPC, is a synthetic phospholipid that plays a significant role in membrane biology and biochemistry. It features a glycerol backbone with two hexadecyl (C16) fatty acid chains attached to the first and second carbon atoms, and a phosphocholine head group at the third carbon. This amphiphilic structure imparts unique properties, allowing DHPC to form lipid bilayers and micelles in aqueous environments, which is crucial for applications in drug delivery and membrane studies. The presence of the phosphocholine group enhances its solubility in water while maintaining hydrophobic characteristics due to the long hydrocarbon chains. DHPC is often utilized in the preparation of liposomes and as a model membrane system for studying membrane dynamics and interactions. Its stability and biocompatibility make it a valuable compound in pharmaceutical formulations and biotechnological applications. Additionally, its racemic nature indicates that it contains both enantiomers, which can influence its biological activity and interactions with other molecules.

Formula: C₄₀H₈₄NO₆P

InChI: InChI=1S/C40H84NO6P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-35-44-38-40(39-47-48(42,43)46-37-34-41(3,4)5)45-36-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h40H,6-39H2,1-5H3

InChI key: InChIKey=MWTIGLPPQBNUFP-UHFFFAOYSA-N

SMILES: C(COP(OCC[N+](C)(C)C)(=O)[O-])(COCCCCCCCCCCCCCCCC)OCCCCCCCCCCCCCCCC

Synonyms:

• (1)-((7-(Hexadecyloxy)-4-oxido-3,5,9-trioxa-4-phosphapentacosyl))trimethylammonium 4-oxide
• 1,2-Di-O-hexadecyl-rac-glycero-3-phosphocholine
• 3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 7-(hexadecyloxy)-4-hydroxy-N,N,N-trimethyl-, hydroxide, inner salt, 4-oxide, (±)-
• 3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 7-(hexadecyloxy)-4-hydroxy-N,N,N-trimethyl-, inner salt, 4-oxide
• <span class="text-smallcaps">D</smallcap><smallcap>L</span>-Dihexadecylphosphatidylcholine
• Choline, hydroxide, dihydrogen phosphate, inner salt, 2,3-bis(hexadecyloxy)propyl ester
• Dihexadecyl lecithin
• Dihexadecyl phosphatidylcholine

1,2-Di-O-hexadecyl-rac-glycero-3-phosphocholine

CAS: 69483-37-0

1,2-Di-O-hexadecyl-rac-glycero-3-phosphocholine is a fine chemical that is used as a versatile building block in the synthesis of complex compounds. It has been shown to be a useful intermediate for the synthesis of research chemicals and reaction components. It can also be used as a speciality chemical due to its high quality and usefulness as a reagent.

Formula: C₄₀H₈₄NO₆P

Purity: Min. 95 Area-%

Molecular weight: 706.08 g/mol

Ref: 3D-D-3230

1,2-Di-O-hexadecyl-rac-glycero-3-phosphocholine

CAS: 69483-37-0

1,2-Di-O-hexadecyl-rac-glycero-3-phosphocholine is a surfactant that is used in the production of emulsions, detergents, and other chemical products. It is also used as a fusogenic agent for the treatment of dry eye syndrome. The adsorption mechanism of 1,2-Di-O-hexadecyl-rac-glycero-3-phosphocholine is photochemical in nature and is dependent on the concentration of sodium dodecyl sulfate (SDS) in solution. At concentrations greater than 0.1% SDS, 1,2-Di-O-hexadecyl -rac -glycero -3 -phosphocholine will adsorb to the surface of an oil droplet and form a micelle layer with an outer hydrophobic layer. This process can be reversed by exposing the system to ultraviolet light or adding more SDS to

Formula: C₄₀H₈₄NO₆P

Purity: Min. 95%

Molecular weight: 706.07 g/mol

Ref: 3D-FD172070