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CAS 69539-53-3

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Etintidine

Description:
Etintidine is a chemical compound classified as a histamine H2 receptor antagonist, primarily used in the treatment of conditions such as peptic ulcers and gastroesophageal reflux disease (GERD). It works by inhibiting the action of histamine at the H2 receptors in the stomach lining, thereby reducing gastric acid secretion. The molecular structure of etintidine includes a substituted imidazole ring, which is characteristic of many H2 antagonists. It is typically administered orally and is known for its relatively rapid onset of action. The compound has a moderate solubility in water and is often formulated in various dosage forms, including tablets and oral solutions. Side effects may include headache, dizziness, and gastrointestinal disturbances, although they are generally mild. As with other medications, it is important to consider potential drug interactions and contraindications when prescribing etintidine. Overall, etintidine represents a significant advancement in the management of acid-related disorders, contributing to improved patient outcomes in gastrointestinal health.
Formula:C12H16N6S
InChI:InChI=1S/C12H16N6S/c1-3-4-14-12(16-8-13)15-5-6-19-7-11-10(2)17-9-18-11/h1,9H,4-7H2,2H3,(H,17,18)(H2,14,15,16)
InChI key:InChIKey=KEDVUOWPLAHMLZ-UHFFFAOYSA-N
SMILES:C(SCCN=C(NCC#C)NC#N)C1=C(C)N=CN1
Synonyms:
  • Guanidine, N-cyano-N′-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]-N′′-2-propyn-1-yl-
  • Etintidine
  • Guanidine, N-cyano-N′-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]-N′′-2-propynyl-
  • N-Cyano-N′-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]-N′′-2-propyn-1-ylguanidine
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