CAS 696-07-1
:5-Iodouracil
Description:
5-Iodouracil is a halogenated derivative of uracil, classified as a pyrimidine nucleobase. Its chemical structure features an iodine atom substituted at the 5-position of the uracil ring, which influences its biological activity and properties. This compound is known for its role as an antimetabolite, particularly in the context of cancer treatment, as it can interfere with nucleic acid synthesis. 5-Iodouracil exhibits moderate solubility in water and is typically stable under standard laboratory conditions. Its molecular formula is C4H3I N2O2, and it has a relatively low molecular weight. The presence of the iodine atom enhances its reactivity and can affect its interaction with enzymes and nucleic acids. In research, 5-Iodouracil is often utilized in studies related to nucleic acid metabolism and the development of antiviral and anticancer agents. Safety precautions should be taken when handling this compound, as with many halogenated organic substances, due to potential toxicity and environmental impact.
Formula:C4H3IN2O2
InChI:InChI=1S/C4H3IN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
InChI key:InChIKey=KSNXJLQDQOIRIP-UHFFFAOYSA-N
SMILES:O=C1C(I)=CNC(=O)N1
Synonyms:- 2,4(1H,3H)-Pyrimidinedione, 5-iodo-
- 2,4-Dihydroxy-5-Iodopyrimidine
- 3H)-Pyrimidinedione,5-Iodo-4(1H
- 5-I-U
- 5-Iodo-2,4(1H,3H)-pyrimidinedione
- 5-Iodo-2,4-dihydroxypyrimidine
- 5-Iodo-2,4-pyrimidinedione
- 5-Iodo-Uraci
- 5-Iodopyrimidine-2,4-diol
- 5-iodopyrimidine-2,4(1H,3H)-dione
- 5IU
- NSC 57848
- Uracil, 5-iodo-
- 5-Iodouracil
- See more synonyms
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Found 10 products.
5-Iodouracil
CAS:Formula:C4H3IN2O2Purity:>99.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:237.985-Iodouracil, 97%
CAS:<p>It is used as an intermediate. It has an antitumor activity. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference ha</p>Formula:C4H3IN2O2Purity:97%Color and Shape:Powder, White to pale creamMolecular weight:237.985-Iodouracil
CAS:<p>5-Iodouracil is a Heterocyclic compound-pyrimidine, intermediate and building block, halo-.</p>Formula:C4H3IN2O2Color and Shape:SolidMolecular weight:237.985-Iodouracil
CAS:<p>5-Iodouracil</p>Formula:C4H3IN2O2Purity:97%Color and Shape: off white solidMolecular weight:237.98g/mol5-Iodouracil
CAS:Controlled Product<p>Applications 5-Iodouracil is a halogenated pyrimidine that can be used in nucleoprotein photo-crosslinking via RNA substitution. 5-Iodouracil is used in thymidine phosphorylase targeted imaging and therapy. Studies show that DNA N-glycosylase MED1 exhibited higher preference for 5-Iodouracil and halogenated bases over non-halogenated ones.<br>References Meisenheimer, K. et al.: Meth. Enzymol., 318, 88 (2000); Klecker, R.W. Jr. et al.: Cancer Chemother. Pharmacol., 48, 407 (2001); Turner, D.P. et al.: Cancer Res., 66, 7686 (2006);<br></p>Formula:C4H3IN2O2Color and Shape:NeatMolecular weight:237.985-Iodouracil
CAS:<p>5-Iodouracil is an irreversible inhibitor of 5-hydroxytryptamine 2B receptor (5-HT2B) that is a group p2 molecule. It has been found to be effective in the treatment of various types of cancer, including colorectal cancer. 5-Iodouracil inhibits cell proliferation by blocking the binding of the growth factor to its receptor on the surface of cells. The drug also inhibits the enzyme activities of human serum albumin and tyrosine phosphatase.</p>Formula:C4H3IN2O2Purity:Min. 97 Area-%Color and Shape:White PowderMolecular weight:237.98 g/mol5-Iodouracil extrapure, 98%
CAS:Formula:C4H3IN2O2Purity:min. 98%Color and Shape:White to off-white, Crystalline powderMolecular weight:238.005-Iodouracil
CAS:Formula:C4H3IN2O2Purity:96%Color and Shape:Solid, White powderMolecular weight:237.984
