CAS 696-45-7

6-Methoxy-4-pyrimidinamine

Description:

6-Methoxy-4-pyrimidinamine, with the CAS number 696-45-7, is an organic compound characterized by its pyrimidine ring structure, which is a six-membered aromatic heterocycle containing two nitrogen atoms at positions 1 and 3. This compound features a methoxy group (-OCH3) at the 6-position and an amino group (-NH2) at the 4-position of the pyrimidine ring. It is typically a white to off-white solid and is soluble in polar solvents such as water and alcohols, owing to the presence of the amino group. The compound is of interest in various fields, including medicinal chemistry, due to its potential biological activities, including antimicrobial and antitumor properties. Its reactivity can be attributed to the functional groups present, allowing for various chemical modifications. Safety data should be consulted for handling, as with any chemical substance, to ensure proper precautions are taken during use.

Formula: C₅H₇N₃O

InChI: InChI=1S/C5H7N3O/c1-9-5-2-4(6)7-3-8-5/h2-3H,1H3,(H2,6,7,8)

InChI key: InChIKey=VELRBZDRGTVGGT-UHFFFAOYSA-N

SMILES: O(C)C=1C=C(N)N=CN1

Synonyms:

• 4-Amine-6-Methoxypyrimidine
• 4-Pyrimidinamine, 6-methoxy-
• 6-Methoxy-4-aminopyrimidine
• 6-Methoxy-4-pyrimidinamine
• 6-Methoxypyrimidin-4-Amine
• Pyrimidine, 4-amino-6-methoxy-
• 4-Amino-6-methoxypyrimidine

4-Pyrimidinamine, 6-methoxy-

CAS: 696-45-7

Formula: C₅H₇N₃O

Purity: 97%

Color and Shape: Solid

Molecular weight: 125.1286

Ref: IN-DA00IBYE

4-Amino-6-methoxypyrimidine

CAS: 696-45-7

4-Amino-6-methoxypyrimidine

Formula: C₅H₇N₃O

Purity: ≥95%

Color and Shape: pale yellow solid

Molecular weight: 125.13g/mol

Ref: 54-OR5359

6-Methoxypyrimidin-4-amine

CAS: 696-45-7

Formula: C₅H₇N₃O

Purity: 97%

Color and Shape: Solid

Molecular weight: 125.131

Ref: 10-F064930

6-Methoxy-4-pyrimidinamine

Controlled Product

CAS: 696-45-7

Applications 6-Methoxy-4-pyrimidinamine is used in the synthesis of carbamothiolacrylamides as selective EP2 antagonists in the treatment of neurodegenerative peripheral diseases. Also used in the preparation of PARP-1 inhibitors.
References Ganesh, T. et al.: ACS Med. Chem. Lett., 4, 616 (2013); Rhee, H. et al.: Bioorg, Med. Chem., 17, 7537 (2009);

Formula: C₅H₇N₃O

Color and Shape: Neat

Molecular weight: 125.13

Ref: TR-M271640