CAS 6960-22-1

6-Methylnicotinamide

Description:

6-Methylnicotinamide is a chemical compound that belongs to the class of nicotinamide derivatives, which are known for their biological significance and potential therapeutic applications. It is characterized by the presence of a methyl group at the sixth position of the nicotinamide structure, which is a pyridine derivative. This modification can influence its pharmacological properties, including its role in cellular metabolism and potential effects on various biological pathways. The compound is typically a white to off-white crystalline solid and is soluble in water and organic solvents, making it versatile for various applications in research and industry. 6-Methylnicotinamide has been studied for its potential antioxidant properties and its role in modulating cellular responses, particularly in the context of inflammation and neuroprotection. Additionally, it may serve as a precursor in the synthesis of other biologically active compounds. As with many chemical substances, handling should be done with care, following appropriate safety guidelines to mitigate any potential risks.

Formula: C₇H₈N₂O

InChI: InChI=1/C7H8N2O/c1-5-2-3-6(4-9-5)7(8)10/h2-4H,1H3,(H2,8,10)

InChI key: InChIKey=IJXDURUAYOKSIS-UHFFFAOYSA-N

SMILES: C(N)(=O)C=1C=CC(C)=NC1

Synonyms:

• 3-Pyridinecarboxamide, 6-methyl-
• 6-Methyl-3-pyridinecarboxamide
• 6-Methylnicotinic acid amide
• 6-Methylpyridine-3-carboxamide
• NSC 69797
• Nicotinamide, 6-methyl-
• 6-Methylnicotinamide
• 6-METHYLPYRIDINE-3-CARBOXAMIDE (6-METHYLNICOTINAMIDE)
• 5-CARBOXAMIDO-2-PICOLINE
• 6-Methylnicotinamide,98%
• 3-Pyridinecarboxamide,6-methyl-(9CI)

6-Methylnicotinamide

CAS: 6960-22-1

Formula: C₇H₈N₂O

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 136.15

Ref: 3B-M2477

6-Methylnicotinamide, 98%

CAS: 6960-22-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₈N₂O

Purity: 98%

Color and Shape: Pale cream, Powder

Molecular weight: 136.15

Ref: 02-A16039

6-Methylnicotinamide

CAS: 6960-22-1

Formula: C₇H₈N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 136.1512

Ref: IN-DA005K29

6-Methylnicotinamide

CAS: 6960-22-1

6-Methylnicotinamide

Purity: ≥98%

Molecular weight: 136.15g/mol

Ref: 54-BUP19117

6-Methylnicotinamide

CAS: 6960-22-1

6-Methylnicotinamide, a nicotinamide derivative, forms co-crystals/salts; spikes in ICH worsen neurological damage.

Formula: C₇H₈N₂O

Purity: 99.46%

Color and Shape: Solid

Molecular weight: 136.15

Ref: TM-T66582

6-Methylnicotinamide

CAS: 6960-22-1

6-Methylnicotinamide

Purity: 98%

Molecular weight: 136.15g/mol

Ref: 54-OR29753

6-Methylnicotinamide

Controlled Product

CAS: 6960-22-1

Applications A nicotinamide derivative that inhibits state 3 respiration in isolated rat liver mitochondria. It is toxic to rat B65 neuroblastoma cells and is used in studies associated with early symptoms of Parkinson's disease.
References O'Sullivan, P.E. et al.: Biochem. Soc. Trans., 24, 61S (1996); Willets, J.M. et al.: Biochem. Soc. Trans., 21, 299S (1993);

Formula: C₇H₈N₂O

Color and Shape: Neat

Molecular weight: 136.15

Ref: TR-M323225

6-Methylnicotinamide

CAS: 6960-22-1

6-Methylnicotinamide is a transport inhibitor that prevents the uptake of fatty acids and growth factors into cells. It has been shown to inhibit the activity of glutamate receptors by blocking the interaction between these receptors and their binding partners, which are called co-agonists. 6-Methylnicotinamide has also been shown to inhibit the synthesis of virus proteins in vitro and in vivo. There is a lack of evidence on its safety profile. 6-Methylnicotinamide may be used to treat hepatitis C and colorectal carcinoma.

Formula: C₇H₈N₂O

Color and Shape: White Powder

Molecular weight: 136.15 g/mol

Ref: 3D-FM25887

6-Methylnicotinamide Iodide

Controlled Product

CAS: 6960-22-1

Applications 6-Methylnicotinamide Iodide is an intermediate in synthesizing Nudifloramide (N925500), which is a metabolite of Niacin (or Nicorinic acid).
References Felsted, R., et al.: J. Biol. Chem., 242, 1274 (1967); Igel, M., et al.: Eur. J. Clin. Pharmacol., 57, 357 (2001); Kashyap, M., et al.: Am. J. Cardiol., 89, 672 (2002); Bottorff, M., et al.: Am. J. Cardiol., 97, 27 (2006);

Formula: C₇H₈N₂O·I

Color and Shape: Neat

Molecular weight: 263.056

Ref: TR-M323230

6-Methylnicotinamide

CAS: 6960-22-1

Formula: C₇H₈N₂O

Purity: 98%

Color and Shape: Solid, White powder

Molecular weight: 136.154

Ref: 10-F068543