CAS 6960-45-8

7-Nitro-1H-indole-2-carboxylic acid

Description:

7-Nitro-1H-indole-2-carboxylic acid is an organic compound characterized by its indole structure, which is a bicyclic compound consisting of a benzene ring fused to a pyrrole ring. The presence of a nitro group at the 7-position and a carboxylic acid group at the 2-position contributes to its unique chemical properties. This compound is typically a yellow crystalline solid and is soluble in polar solvents, reflecting its functional groups' ability to engage in hydrogen bonding. It is often used in biochemical research, particularly in studies involving enzyme inhibition and as a potential building block in the synthesis of various pharmaceuticals. The nitro group can participate in electrophilic substitution reactions, while the carboxylic acid can undergo typical acid-base reactions. Additionally, the compound's structure allows for potential interactions with biological targets, making it of interest in medicinal chemistry. Safety data should be consulted for handling, as nitro compounds can be sensitive and may pose health risks.

Formula: C₉H₆N₂O₄

InChI: InChI=1S/C9H6N2O4/c12-9(13)6-4-5-2-1-3-7(11(14)15)8(5)10-6/h1-4,10H,(H,12,13)

InChI key: InChIKey=BIUCOFQROHIAEO-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=C2C(C=C(C(O)=O)N2)=CC=C1

Synonyms:

• 1H-Indole-2-carboxylic acid, 7-nitro-
• 7-Nitro-1H-indole-2-carboxylic acid
• 7-Nitro-2-indolecarboxylic acid
• 7-Nitroindol-2-carboxylic acid
• 7-nitro-1H-indole-2-carboxylate
• Crt 0044876
• Indole-2-carboxylic acid, 7-nitro-
• Indole-2-carboxylic acid, 7-nitro- (8CI)
• Nsc 69877

7-Nitroindole-2-carboxylic acid, 96%

CAS: 6960-45-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₉H₅N₂O₄

Purity: 96%

Color and Shape: Yellow to orange to pale brown, Powder or lumps

Molecular weight: 205.15

Ref: 02-B20786

7-nitro-1H-indole-2-carboxylic acid

CAS: 6960-45-8

Formula: C₉H₆N₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 206.1549

Ref: IN-DA003NGS

7-Nitro-1H-indole-2-carboxylic acid

CAS: 6960-45-8

7-Nitro-1H-indole-2-carboxylic acid

Formula: C₉H₆N₂O₄

Purity: 97%

Color and Shape: light yellow to yellow solid

Molecular weight: 206.15g/mol

Ref: 54-OR3926

CRT0044876

CAS: 6960-45-8

CRT0044876

Purity: ≥95%

Molecular weight: 206.15g/mol

Ref: 54-BUP16150

CRT0044876

CAS: 6960-45-8

CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.

Formula: C₉H₆N₂O₄

Purity: 98.27% - 98.98%

Color and Shape: Brown Powder

Molecular weight: 206.15

Ref: TM-T6456

7-Nitroindole-2-carboxylic acid

CAS: 6960-45-8

7-Nitroindole-2-carboxylic acid is a molecule that has been shown to inhibit the activity of cytidine deaminase, an enzyme involved in the synthesis of DNA. This drug also inhibits the replication of dna and can be used for the treatment of cancer. 7-Nitroindole-2-carboxylic acid binds to basic proteins and has a helical structure. The affinity constants for this compound have not been reported, but it is thought that hydrogen bonding interactions are involved in its binding.

Formula: C₉H₆N₂O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 206.16 g/mol

Ref: 3D-FN56796

7-Nitroindole-2-carboxylic acid

CAS: 6960-45-8

7-Nitroindole-2-carboxylic acid is a chemical compound that is used as an intermediate for the synthesis of various chemical compounds. It can be used to produce research chemicals, fine chemicals, and building blocks for pharmaceuticals. 7-Nitroindole-2-carboxylic acid is a versatile building block that can be used in the synthesis of many complex compounds.

Formula: C₉H₆N₂O₄

Molecular weight: 206.16 g/mol

Ref: 3D-N-3300

7-Nitro-1H-indole-2-carboxylic acid

CAS: 6960-45-8

Formula: C₉H₆N₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 206.157

Ref: 10-F066301