CAS 69657-51-8

Acyclovir sodium

Description:

Acyclovir sodium is the sodium salt form of acyclovir, an antiviral medication primarily used to treat infections caused by certain types of viruses, particularly herpes simplex virus and varicella-zoster virus. It is characterized by its white to off-white crystalline powder appearance and is soluble in water, making it suitable for intravenous administration. Acyclovir sodium works by inhibiting viral DNA synthesis, thereby preventing the replication of the virus. Its chemical formula is C8H10N5NaO3, and it has a molecular weight of approximately 273.24 g/mol. The substance is typically administered in clinical settings for the treatment of herpes simplex infections, shingles, and chickenpox, especially in immunocompromised patients. Acyclovir sodium is generally well-tolerated, but potential side effects may include nausea, diarrhea, and renal toxicity, particularly with rapid intravenous administration. As with any medication, it is essential to use acyclovir sodium under medical supervision to ensure appropriate dosing and monitoring for adverse effects.

Formula: C₈H₁₁N₅O₃·Na

InChI: InChI=1S/C8H11N5O3.Na/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14;/h3,14H,1-2,4H2,(H3,9,11,12,15);

InChI key: InChIKey=BVOILEATUWMBTI-UHFFFAOYSA-N

SMILES: C(OCCO)N1C2=C(N=C1)C(=O)N=C(N)N2.[Na]

Synonyms:

• 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-, monosodium salt
• 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-, sodium salt (1:1)
• Aciclovir sodium
• Acycloguanosine sodium
• Acyclovir sodium salt
• Acycolguanosine sodium
• Sodium acyclovir
• sodium 2-amino-9-[(2-hydroxyethoxy)methyl]-9H-purin-6-olate
• Acyclovir sodium

Sodium 2-amino-9-((2-hydroxyethoxy)methyl)-9H-purin-6-olate

CAS: 69657-51-8

Sodium 2-amino-9-((2-hydroxyethoxy)methyl)-9H-purin-6-olate

Purity: 98%

Molecular weight: 247.19g/mol

Ref: 54-OR1064046

Acyclovir sodium

CAS: 69657-51-8

Acyclovir sodium is an antimetabolite. Acyclovir sodium inhibits HSV-specified DNA polymerases and prevents further viral DNA synthesis.

Formula: C₈H₁₀N₅NaO₃

Purity: 99.59% - 99.89%

Color and Shape: Solid

Molecular weight: 247.19

Ref: TM-T1454L

2-Amino-1,9-dihydro-9-((2-hydroxyethoxy)methyl)-6H-purin-6-one monosodium salt

CAS: 69657-51-8

Aciclovir is a drug that belongs to the group of antiviral agents and has been used in the treatment of herpes simplex virus (HSV) infections, varicella zoster virus (VZV) infections, and cytomegalovirus (CMV) infections. Aciclovir is a prodrug that is converted into acyclovir, its active form, by hydrolases in cells. This conversion prevents viral DNA replication and transcription by inhibiting the synthesis of viral DNA polymerase, which is required for viral DNA synthesis. Aciclovir is also an inhibitor of toll-like receptor signaling pathways.

Formula: C₈H₁₀N₅O₃·Na

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 247.19 g/mol

Ref: 3D-FA30156