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CAS 696643-14-8

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  • HTS05585
    Targetmol
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    HTS05585

    CAS:
    HTS05585 (Compound Hit-1) is a selective inhibitor of macrophage migration inhibitory factor (MIF) with a Kd value of 0.29 μM determined by microscale thermophoresis (MST) and confirmed through isothermal titration calorimetry (ITC) at 0.32 μM. It suppresses the release of pro-inflammatory factors (TNF-α, IL-6, IL-1β) in macrophages induced by LPS, making it a promising candidate for the study of inflammatory diseases such as sepsis.
    Formula:C18H15N3O
    Color and Shape:Solid
    Molecular weight:289.33

    Ref: TM-T210778