CAS 6971-52-4

3-Methoxy-2-methylphenol

Description:

3-Methoxy-2-methylphenol, also known as o-cresol methyl ether, is an organic compound characterized by its aromatic structure, which includes a methoxy group (-OCH₃) and a methyl group (-CH₃) attached to a phenolic ring. This compound typically appears as a colorless to pale yellow liquid with a characteristic odor. It is soluble in organic solvents and exhibits limited solubility in water. The presence of the methoxy group enhances its reactivity, making it a useful intermediate in organic synthesis and in the production of various chemical compounds. 3-Methoxy-2-methylphenol can also exhibit antioxidant properties and is sometimes utilized in the formulation of certain products, including fragrances and pharmaceuticals. Safety considerations include potential skin and eye irritation, and appropriate handling measures should be taken to minimize exposure. Overall, its unique structural features contribute to its utility in various industrial applications.

Formula: C₈H₁₀O₂

InChI: InChI=1/C8H10O2/c1-6-7(9)4-3-5-8(6)10-2/h3-5,9H,1-2H3

InChI key: InChIKey=SIRZAUFJHUZRTI-UHFFFAOYSA-N

SMILES: O(C)C1=C(C)C(O)=CC=C1

Synonyms:

• 2-Hydroxy-6-methoxytoluene
• 2-Methyl-3-methoxyphenol
• NSC 66560
• Phenol, 3-methoxy-2-methyl-
• o-Cresol, 3-methoxy-
• 3-Methoxy-2-methylphenol

3-Methoxy-2-methylphenol

CAS: 6971-52-4

Formula: C₈H₁₀O₂

Purity: 95%

Color and Shape: Liquid

Molecular weight: 138.1638

Ref: IN-DA00FC71

3-Methoxy-2-methylphenol

CAS: 6971-52-4

3-Methoxy-2-methylphenol

Color and Shape: Solid

Molecular weight: 138.16g/mol

Ref: 54-OR323058

3-Methoxy-2-methylphenol

CAS: 6971-52-4

Purity: ≥95%

Molecular weight: 138.1660004

Ref: 10-F955328

3-Methoxy-2-methylphenol

CAS: 6971-52-4

3-Methoxy-2-methylphenol is a potent inhibitor of cytochrome P450 monooxygenases. It is an effective inhibitor of the CYP1A2, CYP2C9 and CYP3A4 isoforms, with IC50 values ranging from 0.6 to 2.4 μM. 3-Methoxy-2-methylphenol also inhibits vanillyl alcohol oxidase (VAO) and 4-hydroxyphenylacetaldehyde reductase (HPR), which are involved in the metabolism of vanillin or catechol estrogens. The inhibition of these enzymes leads to increased concentrations of vanillin and catechol estrogens in the blood and urine. 3-Methoxy-2-methylphenol has been shown to have synergistic effects when combined with trifluoroacetic acid, which is used as a solvent for organic solvents in pharmaceuticals production. Combined treatment with 3-

Formula: C₈H₁₀O₂

Purity: Min. 95%

Molecular weight: 138.16 g/mol

Ref: 3D-GAA97152